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Agnieszka Noszczyk-Nowak

Abstract

The study presents a comparison of the results received from dogs with dilated cardiomyopathy (DCM) that died during the first 30 d of observation and from dogs with DCM that survived the first 30 d after the ECG. No differences were noted in the duration of QT or QTc in healthy dogs and dogs with DCM. QTcd was significantly higher in dogs with DCM and in dogs with DCM, which did not survive over 30 d of observation and dogs with DCM that died after the 30th d of observation. The presence of T-wave alternans (TWA) was more frequently observed in dogs with DCM (85% of the dogs) that died in less than 30 d during the observation. QTcd and TWA seem to be a useful non-invasive diagnostic tool to anticipate the risk of cardiac death in dogs with DCM.

Open access

Agnieszka Noszczyk-Nowak

Abstract

The aim of this study was to demonstrate the diagnostic accuracy of P-wave dispersion in predicting recurrence of atrial fibrillation in dogs with sinus rhythm restoration after external cardioversion. The study was performed on 15 dogs, which underwent electrical external cardioversion after atrial fibrillation. Nine-lead surface electrocardiogram of each dog was recorded 1 min after the cardioversion process to measure the P-wave duration. Dogs with recurrent atrial fibrillation had significantly higher P-wave dispersion compared to dogs that had a sinus rhythm lasting more than 3 months (9.26 ±2.01 ms vs 20.9 ±2.18 ms, P=0.001). This study suggests that P-wave dispersion analysis in dogs after a successful external electrical cardioversion has diagnostic accuracy to predict the recurrence of atrial fibrillation.

Open access

Agnieszka Noszczyk-Nowak, Marcin Nowak, Urszula Pasławska and Józef Nicpoń

Abstract

Results of supravital and post-mortem observation of embolic-thrombotic complications in dogs, in the course of endotoxaemia induced by pyometra and phlegmonous pneumonia due to infection with Pseudomons aeruginosa, or endomyocarditis caused by Staphylococcus aureus infection were described. Multiorgan embolic-thrombotic complications were diagnosed in all presented cases. Most probably, the complications developed due to thrombocytopoenia secondary to platelet activation and exacerbation of endotoxin-induced DIC syndrome. In all the dogs, a disturbed cardiac rhythm was diagnosed supravitally. The rhythm disturbances might reflect myocardial injury due to presence of bacterial endotoxins in blood. The myocardial injury was confirmed by histopathological examination.

Open access

Agnieszka Noszczyk-Nowak, Marcin Michałek, Adrian Janiszewski, Agnieszka Kurosad, Agnieszka Sławuta, Alicja Cepiel and Urszula Pasławska

Abstract

Introduction: Electrical cardioversion is a therapeutic procedure used to convert various types of arrhythmias back to sinus rhythm. It is used to restore the sinus rhythm in dogs with atrial fibrillation. The effect of the electrical energy used during cardioversion on red blood cells (RBC) is not fully understood. Studies on humans reported lysis of RBC following electrical cardioversion. Similar studies have not been carried out on dogs. The aim of the study was to assess the effect of electrical cardioversion on chosen RBC parameters.

Material and Methods: The study was carried out on 14 large and giant breed dogs weighing from 30 to 84 kg with lone atrial fibrillation (lone AF). Electrical cardioversion was carried out under general anaesthesia by biphasic shock with 70–360 J of energy. Blood was collected at T0 – during atrial fibrillation, prior to cardioversion, and at T1 – 30 min after electrical cardioversion. Complete blood counts as well as total and direct bilirubin concentrations were evaluated. A maximum output of 360 J was used.

Results: In all cases, electrical cardioversion was effective, and no significant changes in the number of RBC and RBC indices were noted. Similarly, there were no statistically significant differences in the levels of total and direct bilirubin.

Conclusion: Electrical cardioversion in dogs led neither to statistically nor clinically significant RBC lysis.

Open access

Jarosław Popiel, Agnieszka Cekiera, Agnieszka Kurosad, Urszula Pasławska, Agnieszka Noszczyk-Nowak and Józef Nicpo

Abstract

The study was an attempt to determine the possibilities of using ovocystatin, a component of a new generation product of natural origin, in local therapy of atopic dermatitis in dogs by suppressing pruritus during illness. Chicken egg cystatin was used locally in the interdigital spaces of forelimbs of dogs used in the experiment. The degree of pruritus and clinical changes in the animals were defined using CADESI-03 scale before and after the beginning of the experiment. The results obtained proved that ovocystatin may be used as a substance suppressing pruritus in atopic dermatitis.

Open access

Agnieszka Noszczyk-Nowak, Marcin Michałek, Ewelina Kałuża, Alicja Cepiel and Urszula Pasławska

Abstract

Introduction: The prevalence of arrhythmias in dogs and the influence of sex, breed, age, and body weight were analysed over a seven-year span.

Material and Methods: In total, 1189 referrals for cardiological examination by electrocardiography were received at one academic centre in Poland between 2008 and 2014. The largest proportion of the examined dogs were cross-breeds with body weight below 25 kg (n = 153, 12.87%), followed by German Shepherds (n = 122, 10.26%), Labrador Retrievers (n = 68, 5.72%), Yorkshire Terriers (n = 63, 5.3%), and Boxers (n = 60, 5.05%). Retrospective analysis was made of 1201 standing or right recumbent electrocardiograms without pharmacological sedation. The prevalence of arrhythmias was examined in terms of sex, age, body weight, and breed of the dogs.

Results: A total of 630 (52.46%) electrocardiograms showed no signs of arrhythmia, but 96 (7.99%) and 475 (39.55%) pointed to physiological and pathological arrhythmias respectively. The most commonly diagnosed type was atrial fibrillation with 33.68% incidence, followed by ventricular arrhythmias (28%), sinus pauses (27.58%), supraventricular arrhythmias (24%), and atrioventricular blocks (22.95%). Pathological arrhythmias were most commonly found in male dogs and in German Shepherds.

Conclusions: Atrial fibrillation predominated, followed by premature ventricular complexes. Male dogs were generally more prone to heart rhythm disturbances.

Open access

Michał Dzięcioł, Agnieszka Noszczyk-Nowak, Katarzyna Michlik, Wojciech Niżański and Grzegorz Dejneka

Abstract

The aim of the study was to evaluate the influence of sildenafil citrate administrated intravaginaly on the blood flow in the bovine uterus during dioestrus. Uterine blood flow was examined in six healthy adult cows. Sildenafil was administrated intravaginaly to each co w between the 6th and 8th d of the ovarian cycle, in the form of vaginal suppositories containing 100 mg of active substance at a dose of 100, 200, or 300 mg per animal. Uterine perfusion was estimated by the colour Doppler examination, and obtained results were analysed with the Pixel Flux Software (Chameleon, Germany). Moreover, cardiovascular parameters were also evaluated. Animals were examined before and five times after drug application (two times at 15 min intervals, and three times at 2 h intervals). A placebo suppository was also given to the cows. The analysis of the intensity and velocity of blood flow in the uterus proved that sildenafil administrated intravaginaly significantly increased blood flow in the uterus and the effect of increased perfusion was observed for 4 h and 30 min after administration. The effect of increased uterine perfusion was observed after low as well as high doses of sildenafil. Significant changes in the cardio-vascular parameters were not detected. There were no changes in the uterine perfusion as well as in cardiovascular parameters after placebo administration.

Open access

Urszula Pasławska, Agnieszka Noszczyk-Nowak and Józef Nicpoń

Abstract

The aim of this study was to evaluate systolic function of left ventricle in dogs with spontaneous mitral regurgitation by estimating the rate of pressure rise in the left ventricle (dP/dt). Ninety-three dogs of different breed and sex, with chronic degenerative valvular disease were examined. All dogs had echocardiography examination with dP/dt estimation assessed from mitral regurgitant jet using continuous Doppler-echocardiography. The dogs were divided into four classes of heart failure according to NYHA class. Results: dogs in NYHA I dP/dt = 2,142 ±1,309, SF=33.6±10.5, EF=66.58± 14; NYHA II dP/dt = 3,062 ±1,798, SF=42 ±10, EF=76.5 ±11.5; NYHA III dP/dt = 3,483 ±2,136, SF=44.2 ±21, EF=75.7 ±13; NYHA IV dP/dt = 4,496 ±1,797, SF=40.6 ±6, EF=70.4 ±16. Dogs with chronic cardiac insufficiency and mitral insufficiency due to chronic degenerative valvular disease had no echocardiograhic evidence of left ventricular systolic dysfunction assessed from mitral regurgitant jet dP/dt.

Open access

Katarzyna Michlik, Agnieszka Noszczyk-Nowak, Urszula Pasławska, Izabela Janus and Józef Nicpoń

Abstract

Electrocardiographic examinations were performed on 45 Silesian breed horses (group K, 3-16-year-old, 16 stallions, 29 mares) and on 25 Polish Primitive breed horses (group P, 1.5-19-year-old, two stallions, six geldings, 17 mares). Einthoven and chest leads were used. P-wave dispersion was electronically evaluated. There was no correlation between P-wave dispersion and other ECG parameters, age, sex, body mass, or month of pregnancy. The average value of P-wave dispersion for all horses was 30.77 ms (SD 3.92 ms), however in particular groups it was: in group P - 31.89 ms (SD 3.07 ms), and in group K - 30.15 ms (SD 4.27 ms). The maximum value of P-wave dispersion in the studied population was 40 ms, in groups P and K - 37,6 ms and 40 ms, respectively. The physiological value of P-wave dispersion for the group of horses was below 45 ms.

Open access

Urszula Pasławska, Agnieszka Noszczyk-Nowak, Adrian Janiszewski and Józef Nicpoń

Abstract

The aim of the study was to estimate prevalence of tricuspid dysplasia (TD) in dogs with respect to breed, age, sex, clinical signs, and echocardiographic findings and to compare this data with literature. TD was found in 15 dogs (6.5% of congenital cardiac disease) of 215 dogs with congenital heart defects. All dogs had right heart enlargement on thoracic radiographs, echocardiography, and electrocardiography. Doppler echocardiography revealed tricuspid valve regurgitation. Seven dogs presented no clinical symptoms to date. TD took the form of Ebstein anomaly in all Labrador Retrievers, one Boxer, and one German Shepherd dog. TD predominated in males (11 males vs. three females). The body weight of the affected dogs, with the exception of the Miniature Schnauzer, exceeded 20 kg. Two dogs (Boxer and Bull Terrier) had additional congenital cardiac lesions in the form of mitral valve dysplasia. The most affected breeds in the study were the Labrador Retriever and Boxer.