Heated gloves have been gaining popularity due to increasing work safety demands. The objective of the present work was to evaluate the effects of the presence of chemical hand warmers in protective gloves. The study involved three types of gloves appropriate for work activities performed in cold environments. Several hand warmer variants were designed, differing in terms of shape and location within the glove, which are of great relevance to the comfort of use. Manual dexterity tests were designed to approximate real conditions of the work environment, allow for simulation of occupational activities, and involve various aspects of manipulation.