This paper presents the concept of topologies and investigation results of switched-capacitor voltage multipliers designed for application in high power systems. The analyzed family of multilevel converters includes established topologies as well as novel concepts. The application of thyristors as well as the invention of novel concepts of multiplier topologies and appropriate control make it possible to achieve high efficiency, high voltage gain, reliable and simple DC-DC converters for high power systems. Based on analytical models of the SCVMs, the paper presents a discussion of the selection of components and the efficiency of the converters as a function of converted power as well as the voltage range on the input and the output side. The results are supported by computer simulations and demonstrative experimental tests.