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  • Author: A. Kováčová x
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B. Kováčová, J. Hasilla and A. Ďurišová

Abstract

This study deals with effect of hospital pharmacist on solving drug-related problems (DRP) in inpatients. The study was carried out as a prospective 5-week study at the Cardiology Clinic, Teaching Hospital, Nitra. The study group included 73 inpatients. Pharmacotherapy of each patient was analysed for DRP within 24-48 h after admission. Information on patients was collected from electronic database, medical reports, communication with attending doctors and ward rounds. Patients’ age, medical history, diagnoses, medication prescribed during hospitalisation and laboratory test results were assessed for further pharmacotherapy rationalisation. Pharmaceutical Care Network Europe (PCNE) classification scheme for DRP V6.2 was used to characterise DRP. There were 36 DRP identified in 37% inpatients (n = 27). The most frequent causes of DRP were dose-related (n = 13; 26%) and use

Open access

B. Kováčová, T. Foltánová, Š. Kónya and A. Ďurišová

Abstract

The aim of this retrospective study was to characterize the acute pain management in patients admitted to Department of Traumatology and to identify the efficacy of analgesic pharmacotherapy. The study involved 83 patients divided into two groups: 52 patients (63%) in Group 1 underwent operation; the remaining 31 patients (37%) in Group 2 had conservative treatment. The characteristics of the patients (diagnosis, analgesic therapy, age, comorbidities, drugs used during hospitalisation, analgesic efficacy) were obtained from electronic database and medical reports by the hospital. Therapy during the first seven days of hospitalisation and the recommended therapy after discharging home were analysed. Records of drug adverse reactions during the whole hospitalisation were monitored. Metamizol was the most frequently prescribed as a primal analgesic. Adequate analgesia solely by metamizol was reached in 20% of all patients; the remaining 80% required increased doses or combination with another analgesic. Metamizol was combined mainly with tramadol, morphine or pethidine. Our study proved metamizol to be an effective analgesic. No clinical manifestation of agranulocytosis was observed in this study.

Open access

A. Kováčová, T. Kvačkaj, R. Bidulský, J. Bidulská, R. Kočiško, J. Dutkiewicz and L. Lityńska-Dobrzyńska

Abstract

The present paper deals with a study on formation of specific substructural features in OFHC copper processed by equal-channel angular pressing (ECAP) considering different strain rate conditions. Since two mechanical tensile testing equipments were being used, strain rate response could be studied in a wide range (both in static and dynamic regimes). Moreover, the copper before tensile testing was subjected to drawing and ECAP, separately, which allows to study the influence of both structural and substructural features (CG vs. UFG structure). Considering the static regime, it was found that UFG materials have advanced properties, showing higher strength and ductility in comparison to their CG counterparts. However, this is valid only to the critical value of the strain rate. In the dynamic regime, mathematical linearized results imply that ultimate tensile strength in samples processed by ECAP increases twice every 10 s−1 rising, however, they lost approximately the same plastic properties than samples after drawing. Differences in the progress of mechanical properties are related to specific structural and substructural features evolved in the material during ECAP processing. Above mentioned features were studied in detail by methods of transmission and scanning electron microscopy (TEM, SEM).

Open access

T. Kvačkaj, A. Kováčová, J. Bidulská, R. Bidulský and R. Kočičko

Abstract

In this study, static, dynamic and tribological properties of ultrafine-grained (UFG) oxygen-free high thermal conductivity (OFHC) copper were investigated in detail. In order to evaluate the mechanical behaviour at different strain rates, OFHC copper was tested using two devices resulting in static and dynamic regimes. Moreover, the copper was subjected to two different processing methods, which made possible to study the influence of structure. The study of strain rate and microstructure was focused on progress in the mechanical properties after tensile tests. It was found that the strain rate is an important parameter affecting mechanical properties of copper. The ultimate tensile strength increased with the strain rate increasing and this effect was more visible at high strain rates (ε˙~102s1) . However, the reduction of area had a different progress depending on microstructural features of materials (coarse-grained vs. ultrafine-grained structure) and introduced strain rate conditions during plastic deformation (static vs. dynamic regime). The wear behaviour of copper was investigated through pin-on-disk tests. The wear tracks examination showed that the delamination and the mild oxidational wears are the main wear mechanisms.

Open access

T. Kvačkaj, R. Kočiško, J. Tiža, J. Bidulská, A. Kováčová, R. Bidulský, J. Bacsó and M. Vlado

The aluminium alloy with chemical conception AlMgSi prepared by PM (powder metallurgy) technology was used. The experiments such as a ring and compression test, ECAR (equal channel angular rolling) for determination of friction coefficient, stress-strain curves and material workability based on analytical methods (Freudenthal, Cockcroft-Latham and normalized Cockcroft-Latham criteria) were performed. Numerical simulations of sample processed by ECAR was carried out by a software Deform 3D with focus on the description of stress, strain fields and workability criteria (Cockcroft-Latham and normalized Cockcroft-Latham). The prediction of fracture formations in a real ECAR sample during processing conditions was also done.