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An access to adequate and safe blood transfusion services is an essential measure of basic healthcare systems. The main purpose of hemovigilance is to enhance the quality and safety of the blood transfusion chains, which are implemented for improving the quality of the blood transfusion chain processes, especially focusing on blood safety. Globally, the framework of hemovigilance is extending as one of the key escalations to the group of the human services administrations, recognizing restructured blood transfusions administrations.

The core objective of this review article is to highlight the objectives of the hemovigilance framework, historical aspects of the hemovigilance framework around the world and the scenario of Nepal. Furthermore, it likewise features the scopes and strategies for implementation of hemovigilance at a hospital. An acceptance and incorporation of the hemovigilance system in an oncology hospital or in any tertiary care hospitals in Nepal can avert the incidence or reappearance of adverse events due to the transfusion identified with the whole transfusion chain process. Globally, including the least developed country like Nepal, the hemovigilance framework must be incorporated and systematized for upgrading transfusion and general society certainty additionally regarding blood and its products. Different strategies must be made for the successful implementation and strengthening the hemovigilance system.

In conclusion, there is an interminable and endless necessity for the effort on hemovigilance; although the rules, regulations, and tools are in place. With the end goal to have a productive hemovigilance framework in the least developed countries like Nepal, an extensive methodology and enormous ideas are required.