R. L. Craciun, Angelica Nela Stavar and Madalina Iliescu
Hepatic lesions induced by drugs include extremely diverse various clinical, biological and histological manifestations that can determine acute or chronic hepatobiliary disease. The term of hepatitis is recommended to be used when there is a histological confirmation. In the last decades a 11 time increase of the hepatic lesions induced by drugs is reported, due both to the increase of the number of used drugs but also by their more frequent recognition.
We carried out a combined retrospective study and longitudinally prospective study that included patients with drug hepatitis. In our study there were 83 cases of drug hepatitis at AINS, which represents 33.46 % of the total number of 248 patients with drug hepatitis. In our study the highest drug hepatitis at AINS were Nimesulid (24 cases), followed by Diclofenac (21 cases), and the fewest at Piroxicam (9 cases). All the cases from the study were symptomatic, showing the increase of the cytolysis enzymes and sometimes cholestasis enzymes (mainly GGT).
The average age at diagnosis was 60.1 years for the 248 patients, being lower for the male gender (57.47 years), compared to the female gender (61.26 years). Women were affected in the highest degree, 69.35% being women and 30.64% men. In our study drug hepatitis by hepatic cytolysis was dominant, more frequent than the cholestatic ones.
Elena Dantes, Anca Hancu, Madalina Iliescu, Ionela Balasa, Alina Busuioc, Claudia Cambrea and Ariadna Petronela Fildan
Background: Miliary tuberculosis is a haematogenuous dissemination of Mycobacterium Tuberculosis (M. tuberculosis) witch involves especially lungs, central nervous system and lymph node. It is a very severe disease with an increased risk of respiratory failure, extensive neurologic sequelas and high mortality. A rapid diagnosis and specific treatment is tremendous important for outcome. Association of strokeis common in tuberculous meningitis (MTB) and could delay the diagnosis and worse the prognosis.
Case presentation: We present a case of 24 years old male, who present asthenia and 20 kilo weight lossduring the last 2 years before admission in hospital. He came in hospital, directly in Intensive CareUnit (ICU) for left hemiplegia followed within hours of fever, repeated focal seizures and coma, reaching a Glasgow score of 6 about 48 hours after admission. Patient requiredorotracheal intubation. The Chest radiograph reveal micro-nodular opacities compatible with miliary TB and the cerebrospinal fluid (CFS) examination led to suspicion of TB meningitis. The Tb etiology was bacteriologically confirmed in sputum and cerebrospinal fluid. After 24 hors, theCT and angio-MRI detected the ischemic lesion in the middle cerebral arterial territory. The injectable antituberculous treatment with 4 drugs was immediately initiated. Parenteral cortichosteroids, anticoagulant, symptomatictreatments were associated. The patient received a very complex and prolonged nursing intervention followed by neurologic and pulmonary rehabilitation in ICU and in the Pneumophtisiology Department. The rehabilitation team identifies the all subjective and objective demands and plan the nursing process of care. When patient gains consciousness the neurologic and pulmonary rehabilitation were started. The evolution was slow, but favorable, after 6 moths of treatment the impairment of left hand movement being the only remaining sign of the past disease.
Conclusions: Collaboration medical team consisting of a neurologist, pulmonologist, infection disease specialist and physiotherapist increased the success rate, diminish the sequelas and improve the quality of life of the patient.
Carmen Oprea, P. Armean, Nicoleta Calota, Elena Roxana Almasan, Elena Valentina Ionescu and Madalina Gabriela Iliescu
The research study aims to assess the quality of physical medicine and rehabilitation (MFR) services offered to the population by specialized sanatoriums and hospitals in Dobrogea, in order to identify some appropriate measures to improve the quality of such services.
The target group (593 respondents) consisted of 6 independent batches, different in number, selected from 6 medical units. The patients responded to a specific questionnaire regarding the quality of MFR services and the collected data were analyzed statistically.
According to the patients′ answers, the medical staff meets their expectations in terms of the information provided at the time of admission, promptitude, kindness, availability, which reflects just one segment of the quality of medical rehabilitation services.
As regards the entity recommending the medical rehabilitation physician, of the total answers, the lowest ratio in the study is held by the answer “family doctor / another doctor”. It thus highlights the poor knowledge of family doctors or other doctors on the therapy benefits specific to medical rehabilitation and therefore the access to such services is not facilitated, a disservice to the patients′ life quality. There is a dependence relation between the level of education and the reason of admission. We see that is not prevention taking the first position, but the pain, which reflects a deficient education for health in all social levels.
Assessing the patient’s satisfaction regarding the mobility facilities in the sanatorium / hospital a percentage of 6.6% patient responded that they are not satisfied. It results that all the 6 partner institutions in the study must evolve to provide decent conditions ensuring the mobility independence to the patients.
Liliana Elena Stanciu, Elena Iuliana Pascu, Elena Valentina Ionescu, E. Circo, Carmen Oprea and Madalina Gabriela Iliescu
Introduction. Glucocorticoids provide a significant resource of scientific progress in medical research, being studied in terms of molecules, genetics, physiopathology at the level of the human body, starting from animal models, with valuable recent discoveries regarding their implications in the human psychic level, stress reaction and the search of new possible therapeutic effects unknown until now. Our work are illustrated the correlations between serum cortisol and body mass index - BMI at old patients under balneal treatment with natural factors from Techirghiol lake. Material and methods. The study monitored 52 patients admitted in Balneal and Recovery Sanatorium of Techirghiol for complex balneal treatment, using mud baths (cold or warm), and physical treatments. The patients were grouped in two batches: batch of cold baths with mud- CMB (15 patients, 28.8%, 6 men and 9 women) and batch of warm baths with mud-WMB (37 patients, 71.2%, 19 man and 18 women). The following issues were statistically analysed: BMI, respectively serum cortisol value variation for each batch studied, both at the time of admission and at the time of discharge; comparative analysis between the two moments for each batch; and the comparative analysis between the two study batches at the time of admission, respectively discharge and the BMI value variation in statistical relation with the serum cortisol values for each batch studies at the time of admission and at the time of discharge. Results. From statistical analysis of the correlation between the body mass index (BMI) of patients included in research in the CMB batch at admission and discharge according to the variations of the serum cortisol level , the two variables (Serum cortisol / BMI) both at admission and discharge are not correlated (r = -0.366; p = 0.180 > α = 0.05; r = -0.035; p = 0.901 > α = 0.05). Also, from statistical analysis of the correlation between the body mass index (BMI) of patients included in research in the WMB batch at admission and discharge according to the variations of the serum cortisol level , the two variables (Serum cortisol / BMI) are correlated at admission (r = -0.406; p = 0.013 > α = 0.05), but are not correlated at discharge (r = 0.200; p = 0.236 > α = 0.05). Conclusions. Previous studies have shown that high levels of adiposity can increase the cortisol stress response. While overweight and obese men showed an increased cortisol response upon each food intake, they can be more susceptible to develop stress associated disorders.
A. I. Tucmeanu, Delia Mioara Popescu, Elena Valentina Ionescu, Carmen Oprea, A. Mociu and Mădălina Gabriela Iliescu
Health management consultancy has become an important source of innovation in management, a bridge between the academic environment, companies and opinion-makers in the field. The objective of this work is to identify the success factors of a consultancy mission within the health system, with the proposal of direct investigation of the hypothesis regarding the positive association between the success of consultancy missions and the consultant’s professional integrity. The survey was carried out during January and February 2017, in Bucharest health units, by applying questionnaires to 68 managers both in the public and private system. The analyzed parameters were: the consultant’s professional integrity, the consultant's competency, the relations with the consultant, the correct definition of the mission, available financial resources, term observance, and related costs. The information obtained was statistically processed using the SPSS system. The answer options to the items in the questionnaire allowed statistical correlations, verifying the survey hypothesis regarding the association between success and professional integrity. Any consultancy mission entails negotiation skills from the consultant, as well as an open attitude, listening and communications skills. The environment created by the manager can even further influence the change acceptance.