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Open access

Bo Zhu, Zhongjian Li, Xinwei Cao, Jianli Liu and Weidong Gao

Abstract

Unlike the normal sizing method, the foam sizing had been proven to be a low-add-on technology. To investigate the effect of foam sizing, film thickness, sized-yarn evenness, and size penetration rate were necessary to evaluate the performances of foam-sized yarns. However, the conventional image analysis of sized-yarn cross sections primarily relied on artificial testing with a low efficiency. This paper proposed a novel dynamic method to measure the sized-yarn properties including film thickness, sized-yarn evenness, and size penetration rate based on yarn sequence images captured from a moving yarn. A method of dynamic threshold module was adopted to obtain threshold for segmenting yarns in the sequence images. K-means clustering algorithm was applied to segment pixels of the images into yarn and background. To further remove burrs and noise in the images, two judgment templates were carried out to extract the information of yarn core. The film thickness, sized-yarn evenness, and size penetration rate were measured based on the yarn core of each frame in sequence images. In order to compare with the experimental results of the dynamic method, the yarn properties of the same samples were tested by static and artificial testing. Results revealed that the proposed method could efficiently and accurately detect the film thickness, sized-yarn evenness, and size penetration rate.

Open access

Li-Wei Gao and Guo-Liang Wang

Abstract

Lung cancer (LC), which includes small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC), is common and has a high fatality rate. This study aimed to reveal the prognostic mechanisms of LC. GSE30219 was extracted from the Gene Expression Omnibus (GEO) database, and included 293 LC samples and 14 normal lung samples. Differentially expressed genes (DEGs) were identified using the Limma package, and subjected to pathway enrichment analysis using DAVID. MicroRNAs (miRNAs) targeting the DEGs were predicted using Webgestalt. Cytoscape software was used to build a protein-protein interaction (PPI) network and to identify significant network modules. Survival analysis was conducted using Survminer and Survival packages, and validation was performed using The Cancer Genome Atlas (TCGA) dataset. The good and poor prognosis groups contained 518 DEGs. miR-190, miR-493, and miR-218 for the upregulated genes and miR-302, miR-200, and miR-26 for the downregulated genes were predicted. Three network modules (module 1, 2, and 3) were identified from the PPI network. CDK1, MCM10, and NDC80 were the core nodes of module 1, 2, and 3, respectively. In module 1, CDK1 interacted with both CCNB1 and CCNB2. Additionally, CDK1, CCNB1, CCNB2, MCM10, and NDC80 expression levels correlated with clinical survival and were identified as DEGs in both GSE30219 and the TCGA dataset. miR-190, miR-493, miR-218, miR-200, and miR-302 might act in LC by targeting the DEGs. CDK1, CCNB1, CCNB2, MCM10, and NDC80 might also influence the prognosis of LC.

Open access

Yaodan Chi, Bin Li, Xiaotian Yang, Tianhao Wang, Kaiyu Yang and Yinhan Gao

Abstract

Crosstalk in wiring harness has been studied extensively for its importance in the naval ships electromagnetic compatibility field. An effective and high-efficiency method is proposed in this paper for analyzing Statistical Characteristics of crosstalk in wiring harness with random variation of position based on Polynomial Chaos Expansion (PCE). A typical 14-cable wiring harness was simulated as the object of research. Distance among interfering cable, affected cable and GND is synthesized and analyzed in both frequency domain and time domain. The model of naval ships wiring harness distribution parameter was established by utilizing Legendre orthogonal polynomials as basis functions along with prediction model of statistical characters. Detailed mean value, mean square error, probability density function and reasonable varying range of crosstalk in naval ships wiring harness are described in both time domain and frequency domain. Numerical experiment proves that the method proposed in this paper, not only has good consistency with the MC method can be applied in the naval ships EMC research field to provide theoretical support for guaranteeing safety, but also has better time-efficiency than the MC method. Therefore, the Polynomial Chaos Expansion method.

Open access

Jun Cheng, Min Li, Ping Gao, Jin-ling Dong and Qi Wang

Abstract

Liver steatosis is a pathological hallmark in patients with chronic hepatitis C (CHC). Increased lipid uptake, decreased lipid secretion, increased lipid synthesis and decreased lipid degradation are all involved in pathogenesis of steatosis induced by hepatitic C virus (HCV) infection. Level of low density lipoprotein receptor (LDL-R) and activity of peroxisome proliferator-activated receptor (PPAR) α is related to liver uptake of lipid from circulation, and affected by HCV. Secretion via microsomal triglyceride transfer protein (MTTP), and formation of very low density lipoprotein (VLDL) have been hampered by HCV infection. Up-regulation of lipid synthesis related genes, such as sterol regulatory element-binding protein (SREBP)-1, SREBP-2, SREBP-1c, fatty acid synthase (FASN), HMG CoA reductase (HMGCR), liver X receptor (LXR), acetyl-CoA carboxylase 1 (ACC1), hepatic CB (1) receptors, retinoid X receptor (RXR) α, were the main stay of liver steatosis pathogenesis. Degradation of lipid in liver is decreased in patients with CHC. There is strong evidence that heterogeneity of HCV core genes of different genotypes affect their effects of liver steatosis induction. A mechanism in which steatosis is involved in HCV life cycle is emerging.

Open access

Li Xican, Gao Yaoxiang, Han Weijuan, Lin Jing, Hu Qiuping and Chen Dongfeng

Abstract

Hylocereus undatus flower is commonly used as food or for medicinal purposes in south China. To study its antioxidant activity and mechanism we used antioxidant and chemical assays to compare two commercial samples from different locations (Shenjing, Qixing). The difference in antioxidant levels corresponded with differences in chemical content (including total phenolics, total flavonoids, kaempferol and quercetin) between Shenjing and Qixing. The antioxidant ability of H. undatus flower seems attributable to total phenolics (mainly total flavonoids). Kaempferol is one of the main bioactive components. H. undatus flower exerts its antioxidant effects through metal chelation and radical scavenging via hydrogen atom (H•) and electron (e) donation.

Open access

Dawei Gao, Chunxia Wang, Yu Jian, Weiwei Li and Pengyu Dong

Abstract

Highly ordered TiO2 nanotube arrays (TiO2 NTs) were prepared by anodic oxidizing method on a surface of Ti substrate. Fabrication of nitrogen-doped TiO2 nanotube arrays (N-TiO2 NTs) was carried out by immersion in ammonia solution. CdS nanoparticles loaded N-doped TiO2 nanotube arrays (CdS/N-TiO2 NTs) were obtained by successive ionic layer adsorption and reaction (SILAR) technique. The samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), photoluminescence (PL) emission spectra and ultraviolet-visible (UV-Vis) diffuse reflectance spectroscopy (DRS). The results indicate that the TiO2 nanotube diameter and wall thickness are 100 nm to 120 nm and 20 nm to 30 nm, respectively. Moreover, the morphology and structure of the highly ordered TiO2 NTs are not affected by N-doping. Furthermore, CdS nanoparticles are evenly distributed on the surface of TiO2 NTs. Finally, the photocatalytic activity of CdS/N-TiO2 NTs was evaluated by degradation of MO under visible-light irradiation. Compared with TiO2 NTs, N-TiO2 NTs, CdS/N-TiO2 NTs exhibited enhanced photocatalytic properties, and the highest degradation rate of CdS/N-TiO2NTs could reach 97.6 % after 90 min of irradiation.

Open access

Qin Zhou, Yu-feng Gao, Xiao-miao Zhao, Fa-ming Pan and Xu Li

Abstract

Objective To investigate the relationship between single nucleotide polymorphisms (SNPs) of the interleukin-4 (IL-4) gene and outcome of hepatitis B virus (HBV) infection in a Chinese Han population.

Methods Total of 501 patients with chronic hepatitis B virus (HBV) infection and 301 controls with selflimiting HBV infection were studied. Three tag SNPs in the IL-4 gene (rs2227284G/T, rs2243283C/G and rs2243288A/G) were genotyped by the Multiplex snapshot technique. The genotype and allele frequencies were calculated and analyzed.

Results The three SNPs showed no significant genotype/allele associations with chronic HBV infection. Overall allele P values were: rs2227284, P = 0.655, odds ratio (OR) [95% confidence interval (CI)] = 1.070 (0.793-1.445); rs2243283, P = 0.849, OR (95% CI) = 0.976 (0.758-1.257); rs2243288, P = 0.659, OR (95% CI) = 1.060 (0.818-1.375). Overall genotype P values were: rs2227284, P = 0.771; rs2243283, P = 0.571; rs2243288, P = 0.902. There were no statistically significant differences between patients with chronic HBV infection and controls. Haplotypes generated by these three SNPs also had no significant differences between the two groups.

Conclusions The three tag SNPs of IL-4 were not associated with the outcome of HBV infection in the Han Chinese population.

Open access

Fuqiang Li, Baotian Pan, Zhongping Lai, Hongshan Gao and Xianjiao Ou

Abstract

The partial bleaching of the luminescence signal prior to deposition results in age overestimation, and can be a problem in delineating fluvial evolution within an OSL chronological framework. The Inner Mongolian reaches of the Yellow River are characterised by a high sediment load and complex sources of sediments. To test the incomplete bleaching occurring in this type of environment, the residual doses and the luminescence signal characteristics of different particle size fractions from 14 modern fluvial sediment samples were investigated. Furthermore, 26 OSL ages derived from drilling cores were compared with 11 radiocarbon ages. Our results show that the residual equivalent doses principally range between 0.16 and 0.49 Gy for silt grains, and between 0.35 and 3.72 Gy for sand grains of modern samples. This suggests that medium-grained quartz has been well bleached prior to deposition, and is preferable to coarse-grained quartz when dating fluvial sediments in this region. The results also show that the De values of coarse-grained fractions display a stronger correlation with distance downstream. In addition, a comparison of OSL and radiocarbon ages from drilling cores establishes further confidence that any initial bleaching of these sediments was sufficient. As a result, we believe that the studied fluvial samples were well bleached prior to deposition.

Open access

Weikai He, Jianxiong Feng, Li Gao, Zhiwei Zhang and Hongwang Lu

Abstract

The Aselliscus Stoliczkanus bat, studied here, has intricately shaped structures surrounding the nostrils. These structures are hypothesised to have influence on animals’ acoustic radiation patterns. Using micro-tomography scanning technique, a 3D digital model of the noseleaf is reconstructed and biosonar beam pattern is analysed using a finite element method based on the 3D noseleaf model. The present research focuses on the conspicuous furrows in noseleaf, and our analysis allows to conclude the followings: a) structural details in noseleaf of Aselliscus Stoliczkanus bat can produce acoustic effects even if it is not adjacent to the nostrils, b) the furrows possess frequency-selective characteristics, c) the furrows have the function to manipulate the direction and width of the outgoing ultrasound wave.

Open access

Chang-Jun Li and Xiang Gao

Abstract

In this paper, we present a new proof of the upper and lower bound estimates for the first Dirichlet eigenvalue λ1D(B(p,r)) of Laplacian operator for the manifold with Ricci curvature Rc−K, by using Li-Yau’s gradient estimate for the heat equation.