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  • Autor: Aija Žileviča x
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Abstract

The current study explored the possibility to attach bacteria and yeasts to micro-silica particles. The aim of the study was to determine possible differences in the speed of rates of turbidity (or speed of adherence) between suspensions of bacteria and yeasts with and without silica micro-particles. Some important findings were demonstrated, which might be promising for developing of a new diagnostic approach to distinguish bacteria from yeasts. Addition of SiO2 beads to bacterial suspensions resulted in a significantly faster decrease of turbidity rates in comparison with corresponding suspensions without SiO2 beads. However, yeasts adhered to silica micro particles quicker in comparison with the speed of adherence of bacteria to silica.

Abstract

Rosacea is a chronic inflammatory skin disorder affecting predominantly adult patients. The aim of the current investigation was to evaluate clinical response by using quality of life assessment before and after an IPL (intensive pulsed light) therapy course for patients sufferring from rosacea treated in the outpatient clinic “Health and Aesthetics” in Rīga during a one-year period (in 2016). All patients presented with typical clinical symptoms of rosacea on the face — acneiform papules, pustules, telangiectasia, centrofacial erythema, and complaints about flushing and burning. In the current study, 100 rosacea patients treated with IPL therapy were selected. Each patient filled in the quality of life questionnaire before and after two courses of IPL therapy. The interval between IPL therapy sessions was one month. The results reflected comprehensive benefit from IPL therapy for all rosacea patients. No serious side effects from IPL therapy were detected. Side effects like mild eythema after procedure (75%), mild oedema (10%), vesiculation (3%), and hyperpigmentation (8%) were completely resolved within four weeks after completion of treatment. In all patients, quality of life assessment showed a statistically significant increase after two courses of IPL therapy.

Optimised Routines for Monitoring of Treated Late Latent Syphilis Patients

Highly sensitive and specific tests are needed in monitoring of the serological activity and efficacy of treatment of late latent syphilis. In a retrospective study, the data of 52 patients who had received treatment for late latent syphilis were analysed in the Clinical Centre of Skin and Sexually Transmitted Diseases, Latvia. The diagnostic sensitivity and specificity was calculated by Syphilis Immunoblot IgG, Treponema Pallidum Immobilisation Reaction (TPIR) and Syphilis Express Diagnosis (SED). The correlation between Treponema Pallidum Immobilisation Reaction (TPIR) and Syphilis Immunoblot IgG, SED and TPIR results were estimated. Syphilis Immunoblot IgG is useful for latent syphilis diagnostics. The values of the synthetic peptide TmpA, TmpN15 and TmpN47 on the Syphilis Immunoblot IgG strip are useful for monitoring of the treatment of late latent syphilis patients.