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The effects of Guarana (Paullinia cupana) supplementation on the cognitive performance of young healthy adults – a Systematic Review

Abstract

Objectives

Guarana (Paullinia cupana) from the Sapindaceae family, native to the Amazon basin, is a natural stimulant herb that can be found in popular energy drinks, pharmaceutical shops or local herb shops. With the use of natural health products increasing, guarana has gained a fair amount of popularity in the past years. In this systematic review, we examined the effects of guarana supplementation on cognitive performance. A secondary objective was to compare guarana with caffeine on cognitive performance.

Methods

Searches were made in PubMed using the terms ‘Guarana’ or ‘Paullinia cupana’. Filters focused on Controlled Clinical trials. Inclusion criteria were met by studies using interventions with guarana, while focusing on guarana’s effects on cognition. Participants needed to be young, healthy adults. Studies not published in English or Greek were excluded. The last date of our search was March 7, 2019.

Results

A total of 29 studies were identified and screened. After screening, 17 studies were excluded. The remaining 12 studies were found eligible for data extraction. After reading the full text of the 12 studies, 3 studies were excluded. In the end, 9 studies were found eligible for our systematic review (n = 369 participants). In these studies, guarana showed to improve reaction time and accuracy of performance at cognitive tasks. No significant differences were found when comparing guarana with caffeine.

Conclusion

Guarana seems to improve reaction time and accuracy of performance at tasks, but no significant effects were found when compared with caffeine. High quality randomized controlled clinical trials with a low risk of bias are needed to further study the herb.

Open access
Anxiety In A Dental And Maxillofacial Surgery Consulting Room: Does Previous Experience Matter?

Abstract

Objectives

To explore the associations between previous dental visits and dental anxiety among patients presenting at the dental and maxillofacial surgery clinic of Department of Dental and Maxillofacial Surgery, Federal Medical Centre, Birnin Kebbi, Nigeria.

Materials and methods

This study was a cross-sectional study conducted among 172 patients. Study instrument was a 9-item structured questionnaire, which obtained information about the participants regarding their: demographic profile; previous dental experience; and dental anxiety status in a dental and maxillofacial surgery consulting room. Data collected were analyzed using the SPSS Version 20 Software. Associations between variables were evaluated using Chi-square statistics using a p < 0.05 to determine the level of statistical significance.

Results

Roughly, six-tenth (57.6%) of the participants were males. The observed prevalence of dental anxiety among the participants was 47.7%. A history of pain experience during past dental treatment as well as a history of past dental visit were found to have statistically significant relationships with participants’ dental anxiety status (p-values < 0.05). However, the frequency of previous dental visits, a history of past dental treatment, and a history of use of intraoral injections in the course of past dental treatment were found to have no statistically significant relationship with participants’ status of dental anxiety (p-values > 0.05). Finally, the prevalence of dental anxiety among the groups of female folks with “a history of previous visit to a dentist” and “a history of pain experience in the past dental treatment” were found to be significantly higher than that observed among similar groups among the male folks (p-values < 0.05).

Conclusion

Previous experience of pain plays a major role of influence over dental anxiety experience among patients. Hence, dental practitioners need to pay more attention towards dental anxiety management among patients, especially women.

Open access
Psychometric properties of the Bangla version of the Kessler Psychological Distress Scale (K6)

Abstract

Objective

The 6 item Kessler Psychological Distress Scale (K6) is a screening tool for psychological distress with robust psychometric properties; however, information is lacking on such properties of the scale on its Bangla version. The aim of this study was to evaluate the psychometric properties of the Bangla version of the K6 scale in young people.

Method

A self-administered questionnaire survey was conducted between August 2017 and April 2018 among 718 students aged 13-24 years (45% females) from Dhaka, Bangladesh. Psychological distress was assessed using the Bangla K6. The survey was repeated in a week. Statistical software AMOS 25 and Stata SE 14 were used to conduct the analyses.

Results

The Bangla K6 scale demonstrated an acceptable internal consistency with high Cronbach alpha. Principal component analysis confirmed a single-factor structure of the scale. Confirmatory factor analysis supported the one-factor structure of the scale with adequate fit to the survey data. Test-retest reliability was acceptable with good reliability coefficients. Receiver operating characteristic analyses showed good prediction of depressive symptoms by the Bangla K6 scores.

Discussion

This study provides an initial support for the Bangla K6 scale as an acceptable instrument to assess psychological distress of Bangla-speaking young people. More research is needed to understand our ability to identify vulnerable individuals, whose native language is Bangla and who are in need of mental health support.

Open access
Adherence to Mediterranean diet and risk of depression later in life. A cross sectional study in East Attica, Greece

Abstract

Objectives

The purpose of the present study was to estimate the prevalence of depression later in life in an urban area and to investigate the associations between possible risk and protective factors including adherence to a Mediterranean diet.

Methods

A cross-sectional study was conducted among the active members of the open day-care centres for older people, in East-Attica, Greece. An anonymous questionnaire was developed to collect basic demographic and medical data, the Geriatric Depression Scale (GDS-15) was applied to screen the elderly for depressive symptoms, the Athens Insomnia Scale (AIS) was used to quantify sleep disturbances and adherence to the Mediterranean diet was evaluated using the Mediterranean Diet Score (MDS). Statistics was processed with SPSS 24.0.

Results

154 older adults took part in the study. According to GDS-15, 24.7% (21.4% moderate and 3.2% severe type) screened positive for depressive symptoms. 29.9% of the participants reported inadequate sleep, based on AIS. Depression and insomnia in older participants were more frequent in women than in men, in lower educated, in participants with lower monthly income and in older people with comorbidity (p < 0.05).

MDS revealed that adherence to a Mediterranean diet was moderate for 64.3% of the participants, and it was high for 34.4%. Depression diagnosed by a physician, was strongly associated with MDS (p = 0.035) and AIS (p = 0.001). Logistic regression analysis results revealed a diet higher in vegetables and lower in poultry and alcohol was associated with decreased likelihood of developing symptoms of depression later in life.

Conclusions

Our results support that depression in older adults is common and strongly associated with several risk factors. Adherence to a Mediterranean diet may protect against the development of depressive symptoms in older age. Moreover, not only diet but also sleep-deficiency might contribute to the depression later in life.

Open access
Positive impact of clinical pharmacist interventions on antipsychotic use in patients on excessive polypharmacy evidenced in a retrospective cohort study

Abstract

Objectives

Although antipsychotic prescribing in elderly patients using polypharmacy has not been studied in well-designed clinical trials and meta-analyses, there is an urgent need to monitor prescribing practice in this population. One of the possible approaches to optimize pharmacotherapy may be the involvement of clinical pharmacists (CPs). The aim of this research was to examine whether the involvement of a CP can improve treatment guidelines adherence and change the total number of medications per patient in older patients who are treated with excessive polypharmacy that includes antipsychotics.

Methods

This cohort retrospective study included older patients (65 years or older) treated with at least one antipsychotic and excessive polypharmacy (10 or more medications concurrently) between 2012 and 2014 in primary care. The main outcome measures were antipsychotic treatment guidelines’ adherence and the total number of medications per patient after the CP’s interventions. Only interventions including antipsychotics were studied in detail (i.e., discontinuation, switching, initiation, dose adjustment, change of another medication because of a drug-related problem). Data on diagnoses, patient pharmacotherapy and the CP’s interventions were obtained from clinical records and medical reviews. Age and acceptance of the CP’s interventions were used as predictive factors for antipsychotic treatment guidelines’ adherence.

Results

Forty-nine patients were included. The CP suggested 21 different interventions of which nine (42.8%) were accepted by the general practitioners. The number of medications that patients received decreased after the CP’s interventions (N of medications before: 15.4; N of medications after: 12.0, p < 0.05). The acceptance of the CP’s recommendations, but not age, improved antipsychotic treatment guidelines’ adherence (p = 0.041).

Conclusions

These results show that a collaborative care approach including a CP in primary care significantly improved the adherence to treatment guidelines. The results also support the implementation of this service in the Slovenian healthcare system, although more studies are needed.

Open access
Impact of River Bank Erosion on Mental Health and Coping Capacity in Bangladesh

Abstract

Objectives

Riverbank erosion is a regular phenomenon that displaces millions of people every year worldwide. More than 100,000 people are displaced due to river erosion every year in Bangladesh. People have to resettle in a different place leaving behind their property and familiar environment. This transformation with economic crisis acts as a major stressor for the persons and their families. However, people may adapt different strategies to adapt this difficult situation and keep themselves healthy. They might have higher coping skills due to what they had to endure. This study aimed to find out the difference in the mental health status and coping strategies among the river bank erosion affected and non-affected people in Bangladesh

Methods

We interviewed 100 adult respondents, of whom 50 had been affected and 50 had never been affected by river erosion in Bangladesh. All the participants completed self-report sociodemographic questionnaires; their mental state was evaluated with the Bangla version of the General Health Questionnaire-12 (GHQ-12) and the coping was measured using the COPE scale.

Result

The mental health well-being score of the affected group was significantly lower than the non-affected group. However, accounting for gender, income and age, the affected group had lower mean score in coping (55.86) then the non-affected group (64.04). However, the difference was not statistically significant.

Conclusions

Riverbank erosion is a major natural disaster in Bangladesh that makes people vulnerable to mental disorder. However, it receives less attention; we hope this study will stimulate future researcher to explore mental state and coping mechanism in multiple perspectives and develop evidence-based service for them.

Open access
The Vulnerability and Resiliency of Childhood

Abstract

Life is full of stressors, which have to be confronted efficiently to grow up. However, reaction to stressors is personalized, complex and coordinated. Vulnerable persons adjust poorly to stressors and express inappropriate responses, while resilient persons practice adaptive physiological and psychological responses. Promotion of resiliency is an intricated issue, which demands strategies at both macro and micro-level. Microlevel strategies are focused on the community, family and individual level, while macrolevel strategies formulate the principles. Nevertheless, prediction of vulnerability and resiliency is really a challenge, as different persons facing same stressors react differently. Some are growing as resilient and others as vulnerable. We aimed to discuss resiliency, vulnerability, importance in relation to health outcome, promotion of resiliency and controversies of vulnerability and resiliency.

Open access
Can reading too much make me run mad? Exploring students’ assumptions and academic performance

Abstract

Objectives

To determine the prevalence of the assumption that ‘reading too much’ could cause madness (i.e., severe mental illness) among medical, nursing, and community health students, and also explore the relationship between these students’ status on this assumption and their academic performance.

Methods

This study was a cross-sectional study conducted among a convenient sample of medical, nursing, and community health students (n = 122) studying within the Usmanu Danfodiyo University Teaching Hospital campus, Sokoto, Nigeria. Study tool was a paper questionnaire, which obtained information on the demographic profile, awareness of ‘madness’, assumption that ‘reading too much’ is a cause of madness, and self-rating of the participants’ academic performance in their current course of study. Data collected was analysed using the SPSS version 20 software. Test of associations between variables were done using Chi square test.

Results

The mean age of the 122 respondents was 27.3 years, majority (61.5%) of them were males, and 53.3% were medical students. More than half of the surveyed nursing students (54.2%) and community health students (55.6%), unlike the surveyed medical students (24.6%), had the assumption that reading too much could make them run mad. There was no statistically significant relationship between the assumption that ‘reading too much’ is a cause of mental illness and academic performance of the respondents.

Conclusion

Assumption that reading too much could cause madness is a fairly common phenomenon among the surveyed tertiary school students, irrespective of their level of academic performance. There exists the need to disabuse the minds of tertiary school students from the assumption that reading too much could make one run mad.

Open access
The Impact of Childhood Trauma and Depressive Symptoms on Body Mass Index

Abstract

Objectives

Obesity is associated with several somatic diseases and increased psychological burden. This study focused on two potential psychological predictors of the body mass index (BMI), childhood trauma and depressive symptoms.

Methods

We used three independent populations: two general population samples (Study of Health in Pomerania, SHIP-2, N = 1,657; SHIP-TREND-0, N = 3,278) and one patient sample (GANI_MED, N = 1,742). Childhood trauma was measured with the childhood trauma questionnaire (CTQ) and depression with the Beck Depression Inventory (BDI-II) in SHIP-2 and the Patient Health Questionnaire (PHQ-9) in SHIP-TREND-0 and GANI_MED. We investigated the impact of childhood trauma and depression on BMI. Furthermore, we used mediation analysis to assess whether depression was a significant mediator on the path from childhood trauma to adult BMI in each of the three samples.

Results

In all the three populations, depressive symptoms exhibited a significant association towards higher BMI (p < 0.05). Childhood trauma was positively associated with BMI with significant associations in SHIP-TREND-0 (p < 0.001) and GANI_MED (p = 0.005). The relationship between CTQ and BMI was significantly partially mediated (p < 0.05) by depressive symptoms in SHIP-TREND-0 (38.0%) and GANI_MED (16.4%), in SHIP-2 results pointed in the same direction. All the trauma sub-dimensions, except sexual abuse, exhibited at least one significant association towards increased BMI in one of the samples.

Conclusions

Childhood trauma and depressive symptoms may be considered as causes of obesity. These results suggest that psychological treatments against obesity should address childhood maltreatment as well as depressive symptoms in their diagnostic assessment and could facilitate psychotherapeutic treatment when necessary.

Open access
A systematic review of mindfulness based interventions for children and young people with ADHD and their parents

Abstract

Objective

Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent disorders in childhood, which may pose risks in later life such as academic underachievement and anti-social behaviour. It has been suggested that mindfulness-based interventions (MBI) may contribute to positive outcomes with child and adult populations. In this article, we aim to systematically review the literature regarding the effectiveness of MBI on both children with ADHD and their parents.

Method

Seven databases were searched using the PRISMA criteria and included peer-reviewed journals and grey literature.

Results

Ten studies met the inclusion criteria. Findings suggested that MBI had positive results in addressing attention deficits in children with ADHD, but in terms of hyperactivity, the evidence was conflicting. MBI interventions also appear to effectively address parental stress and family functioning. However, the rating from the quality assessment showed several methodological limitations.

Discussion

The current evidence on the impact of MBI on ADHD symptoms is non-conclusive. However, promising data indicated the potential for MBI in addressing parental stress and family functioning. Further research is recommended to overcome the current methodological limitations.

Open access