Purpose: To assess body composition and obesity in individuals with spinal cord injury (SCI) who practice and do not practice physical activity using body mass index (BMI) and bioelectrical impedance analysis (BIA). Methods: 39 patients with SCI went through BIA evaluation and BMI was assessed. Patients were divided into four groups according to injury level (paraplegia or tetraplegia) and physical activity achievement (active or inactive). Results: 22 individuals with paraplegia (7 active and 15 inactive) and 17 with tetraplegia (5 active and 12 inactive) were evaluated. BMI, fat percentage, fat mass, lean tissue mass, total body water (TBW), and TBW percentage were assessed in groups. Tetraplegic inactive groups showed higher fat percentage featuring obesity. For paraplegic active group mean fat percentage was 19.61% (±9.27) and mean fat mass was 16.66 kg (±9.71) and for paraplegic inactive group fat percentage was 23.27% (±5.94) and fat mass 18.59 kg (±7.58). For tetraplegic groups in active group the fat percentage was 17.14% (±6.32) and fat mass was 11.22 kg (±5.16) and for inactive group mean fat percentage was 33.68% (±4.74) and fat mass was 25.59 kg (±2.91). When paraplegic and tetraplegic inactive groups were compared differences were observed in fat percentage (p = 0.0003) and fat mass (p = 0.0084). Also, when tetraplegic groups (activeXinactive) were compared differences in percentage (p = 0.0019) and fat mass (p = 0.034) were observed. Only for the paraplegic inactive group BMI result was higher than 25 kg/m2. Conclusion: BMI does not discriminate between obesity levels in individuals with SCI and physical activity can improve body composition and prevent obesity in SCI patients.
Alternating current methods have the potential to improve the measurement of electrodermal activity. However, there are pitfalls that should be avoided in order to perform these measurements in a correct manner. In this paper, we address issues like the choice of measurement frequency, placement of electrodes and the kind of electrodes used. Ignoring these factors may result in loss of measurement sensitivity or erroneous measurements with artifacts that contain little or no physiological information.
We present a novel method to detect proximal volume changes based on the impedance plethysmogram (IPG) measured from limb to limb with two electrode pairs symmetrically placed at distal areas of the upper or the lower limbs. Since the measurement is sensitive to changes along the whole current path, this method allows us to detect changes in arteries that are more proximal to the torso than the measurement sites. Our results show that the Pulse Arrival Time (PAT) measured from the R peak of the ECG to the hand-to-hand IPG is close to the PAT to the elbow whereas the PAT measured from the R peak of the ECG to the foot-to-foot IPG is close to the PAT to the knee. This opens new avenues for noninvasive cardiovascular measurements based only on electrodes in contact with hands or feet.
Electrical Impedance Tomography (EIT) has been proposed as a method for imaging and localising epileptic activity in the brain. No existing EIT system meets all of the requirements for effective imaging of epilepsy. A parallel EIT system, employing frequency division multiplexing, is described, which is optimised for measuring impedance changes during epilepsy. The system is capable of imaging short duration, spontaneous events in a saline filled tank, using as little as 1ms of recorded data. In-vivo impedance measurements recorded during epilepsy in a rat model are presented.
The present study determines the effect of compression over bioimpedance of healthy soft tissue (in-vitro and in-vivo). Electrical impedance spectroscopy (EIS) is a promising tissue characterization and tumor detection technique that uses tissue impedance or admittance to characterize tissue and identify tissue properties as well as cell structure. Variation in EIS measurements while applying pressure suggests that compression tends to affect soft tissue bioimpedance. Moreover, the displacements in tissue caused by applied compression may provide useful information about the structure and state of the tissue. Thus combining the changes to the electrical properties of tissue resulted by applied compression, with the changes in tissue displacements caused by applied compression, and consequently measuring the effect that electrical and mechanical properties have on each other, can be useful to identify tissue structure. In this study, multifrequency bioimpedance measurements were performed on in-vitro and in-vivo soft tissue at different pressure levels. Increasing compression on the in-vitro tissue results in an increase in both extracellular resistance and membrane capacitance while it causes a reduction in the intracellular resistance. However, as the compression over the in-vivo samples increases, the intracellular and extracellular resistance increase and the membrane capacitance decreases. The in-vivo measurements on human body are also tested on contra-lateral tissue sites and similar tissue impedance variation trends are observed in the contra-lateral sites of human body. The evidence from these tests suggests the possibility of using this EIS-Pressure combined measurement method to improve tumor detection in soft tissue. Based upon the observations, the authors envision developing an advanced model based upon the Cole model, which is dependent on tissue displacements.
Impedance measurements that involve the human body are affected by the capacitance between the body and earth ground. This paper describes a fast method to estimate that capacitance at 10 kHz, which is valid for impedance analyzers intended to measure ungrounded impedances. The method does not require any external component other than two common capacitors and two conductive electrodes in contact with the body.
There is a need for isolated current sources for use in selected bioimpedance measurement circuits. The requirement for good isolation is particularly important in medical settings because of safety concerns. A new circuit for producing voltage-controlled current is presented. Measurements have been made on a prototype and simulations have been done on a SPICE model. The presented circuit is an H-bridge where the output devices are the output photodiodes of high-linearity optocouplers. Five operational amplifiers, four high linearity optocouplers, and passive components are used. Output current capability is ±35 μA with an output impedance that is more than 1 M Ω. It is possible to achieve bandwidths above 1 MHz for small load impedances. This circuit is well suited for medical applications thanks to the isolation in the optocouplers.
The impedance, capacitance and conductance of deionized water-glucose polar solution is measured by employing impedance spectroscopy and a quasi-oscillatory nature of variation with glucose content in the solution is observed. Such quasi-oscillatory nature is attributed to the randomly distributed water-water, water-glucose and glucose-glucose dipole interactions at the molecular level in the solution. A relevant analytical model is developed on the basis of such random distribution of the molecular dipoles and the experimental data agree well with those obtained from the theoretical model. The electrical parameters are measured in the frequency range of 100Hz to 4MHz for the volume fractions of glucose with respect to water in the range of 0.1 to 0.5. The impedance, capacitance and conductance are obtained to be in the range of 1.03 kΩ – 112 kΩ, 34.9 pF – 1.66 nF, and 8.95 μS – 52.9 μS respectively for the glucose volume fraction range considered.