The NW–trending Three Pagodas shear zone exposes a high–grade metamorphic complex named Thabsila gneiss in the Kanchanaburi region, western Thailand. The quartz mylonites within this strike–slip zone were selected for strain analysis. 2–dimensional strain analysis indicates that the averaged strain ratio (Rs) for the lower greenschist facies increment of XZ– plane is Rs = 1.60–1.97 by using the Fry’s method. Kinematic vorticity analysis of the quartz mylonites in the shear zone showed that the mean kinematic vorticity number of this increment is Wk = 0.75–0.99 with an average at 0.90 ±0.07. The results implied that the quartz mylonites within the Three Pagodas shear zone have a dominant simple shear component of about 72% with a small pure shear component. A sinistral shear sense is indicated by kinematic indicators from macro– to micro–scale. We conclude that the Three Pagodas shear zone deformed in the process of sinstral shear–dominated transpression, which is similar to the Mae Ping shear zone in the north.