Objective: To sort out and analyze on acupuncture-moxibustion (AM) based clinical trials literature for hyperlipidemia (HLP) so that to find out the characteristics of AM, by which the more rational strategy of AM for HLP could be made.
Methods: We searched clinical trial paper on hyperlipidemia by AM in the main English and Chinese databases, included those met the eligibility, and employed the metrologic method to analyze and summarize the AM manipulation features.
Results: (1) A total of 124 articles were included with 128 times of AM methods in this study. (2) AM methods were broadly distributed: 29 articles on mild moxibustion, 24 on manual acupuncture, 21 on electro-acupuncture, 6 on magnetic needle, 6 on herbal pastry-insulated moxibustion (HPIM), 4 on warming needle moxibustion (WNM), 3 on acupoint injection, 2 on laser exposure, 1 on intradermal imbedding needle, and 1 on needle-knife. (3) characteristics of AM: manual acupuncture focuses on the manipulation of reinforcement or reduction by inserting/lifting or twisting in different directions, based on pathopattern differentiation (deficiency or repletion). Electro-acupuncture, which is supposed to have no difference on reinforcement/reduction, mostly choose dilatational wave at a frequency between 2~100Hz, with around 30minutes needle-retainment and 30 sessions for the whole treatment; mild moxibustion takes around 10 minutes for each session on each acupoint; HPIM usually takes 3 to 5 cones for each session on each acupoint; WNM usually takes 30 minutes for each session, by being administered every day or every other day, for total 30 session.
Conclusion: Currently the major used AM methods for HLP are manual acupuncture, electro-acupuncture and mild moxibustion. By turns they pay more attention on reinforcement/reduction, wave form and frequency, and dosage of moxibustion, respectively.
1 Chinese Adult Serum Lipid Abnormality Prevention and Treatment Committee. Guidelines of prevention and treatment on adult serum lipid abnormality. Chinese Journal of Cardiology 2007,35(5):390-413.
2 Li-Ming WANG, Yi-Chong LI, Yu-Fang BI, et al. The epidemic characteristics of blood fat abnormality in Chinese adults in 2010. Chinese Journal of Preventive Medicine 2012,46(5):414-418.
3 Yin-Li, Zhi-Hong CHEN, Bei-Fang ZHOU, et al. The predictive role of blood fat and lipoprotein on detecting cardiovascular events in middle-aged group. Chinese Journal of Cardiology 2004,32(7):643-647.
4 Arrow WS. Management of hyperlipidemia with statins in the older patient. Clin Interv Aging,2006,1(4):433-438.
5 Fang LI, Yan NONG. Overview of acupuncture treatments on hyperlipermia. Journal of Jiangxi University of Traditional Chinese Medicine 2010, 22,(4):87-91.
6 Zhan-Qiang MA. Meta analysis on the safety and effectiveness of acupuncture on hyperlipemia. Henan Traditional Chinese Medicine 2012,32(10):1398-1401.
7 Yue-Chun HOU, Yue ZHANG, Gui-Ying ZHUANG. Laser treatment on acupoints for hyperlipermia. Chinese Journal of Rehabilitation 2006, 21,(1):11.
8 Yue ZHANG. A clinical study on the effect of warm-needlemoxibustion on Zu San Li for hyperlipermia. Shan Dong University of Traditional Chinese Medicine 2005:7.
9 Yuan-Ming LING. Clinical study on the effect of warm-needlemoxibustion for hyperlipermia with pathopattern of spleen deficiency and phlegm retention. Guang Dong University of Traditional Chinese Medicine 2011:16.
10 Huan WU. Clinical and experimental studies on Fenglong point injection for hyperlipermia. Hubei University of Traditional Chinese Medicine 2013:22.
11 Hui DUAN, Xiao-Hong ZUO, Qi-Jie ZHANG. Needle-knife treatment for simple obesity with hyperlipermia. Chinese Acupuncture (Specific volume on needle-knife) 2010; 21:1-4.
12 Xiao-Ling QIU, Hao QIU, Shen-Rong WU, et al. Clinical observation on acupuncture treatment for simple obesity with hyperlipermia. Zhejiang Journal of Traditional Chinese Medicine 2006;41(4):220-221.
13 Hui ZHAO. Clinical study on acupuncture for hyperlipermia based on point selection by pathopattern diagnosis. Chinese Primary Health Care 2002,16(10):54-55.
14 Ming CHEN. Clinical study on electro-acupuncture on Fenglong point for hyperlipermia. Hubei University of Traditional Chinese Medicine 2006:19.
15 Hui-Fang ZHANG, Ling-Ling WANG, Ming-Yun MA. The effects of mild moxibustion on blood fat, plasma oxidized LDL, ET-1 and NO in primary hyperlipermia patients. Lishizhen Medicine and Materia Medica Research 2013,24(6):1521-1522.
16 Ming-Yun MA, Jing-Feng JIANG, Xiao-Yun ZHOU, et al. The effects of mild moxibustion on bloodf at, ET/NO and TXB2/6－ Keto－PGF1αin hyperlipermia patients. Liaoning Journal of Traditional Chinese Medicine 2012,39(10):2052-2054.
17 Wei LI. Optimization of electro-acupuncture on Fenglong for hyperlipermia and its mechanism.Beijing University of Traditional Chinese Medicine. 2006:38.
18 Hai-Hui XING, Ling-Ling WANG, Jian-Bin ZHANG, et al. The effects of mild moxibustion on hypercholesteremia patients based on different time parameters. Chinese Acupuncture 2010,30(11):937-940.
19 Zhong-Jie CHEN, Zhong-Chao WU, Cai-Feng LI, et al. The effects of different moxibustion time on hyperlipermia. Chinese Acupuncture 2012,32(11):995-999.
20 Hui-Fang ZHANG, Ling-Ling WANG, Jian-Bin ZHANG, et al. Clinical study on the moxibustion effects on regulating blood fat. World Journal of Traditional Chinese Medicine 2013,8(8):871-879.