Prevalence and Risk of Dupuytrèn Disease in Patients with Diabetes Versus Non-Diabetic Patients

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Objectives: The aim of the study was to calculate the prevalence rates and risk of appearance of Dupuytrèn disease in diabetic patients with both type-1 (T1DM) and type-2 diabetes (T2DM). Material and Method: 384 patients were analysed, of which 47 had T1DM, 140 had T2DM and 197 were non-diabetic controls. Diabetic patients were followed at the Clinical Center for Diabetes, Nutrition and Metabolic Disease of the Emergency Clinical County Hospital and Department of Dermatology in Oradea, all of them having a diabetes duration of at least 5 years. Results and Conclusions: The risk of Dupuytrèn’s disease is over 4.5 times greater in patients with type-2 diabetes. The risk of Dupuytrèn’s disease is 3-6 times greater in patients with micro-vascular complications.

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  • 1. Brunson J-G Gall EA. Concepts of Disease.A Textbook of Human Pathology. The Macmillan Co. New York 1971.

  • 2. Mikkelsen OA. The prevalence of Dupuytren’s contracture in Norway. A study in a representative population sample of the municipality of Haugesund. Acta Chir Scand 138: 695-700 1972.

  • 3. Burrows NP Lovel CR. Disorders of Connective Tissue. In: Rook’s Textbook ofDermatology. 8th Edition. Burns T Breathnach S Cox N Griffiths C (Eds) Wiley-Blackwell Chichester Vol.3 pp 45.45 2010.

  • 4. Hueston JT. Dupuytren diathesis. In: Dupuytren's Disease. McFarlane RM (ed). Churchill Livingstone Edinburgh pp 246-249 1990.

  • 5. Conessa C. Contribution a l'etude des perturbations vasculaires dans la maladie de Dupuytren PhD Thesis Lyon 1981.

  • 6. Heathcote JG Cohen H Noble J. Dupuytren’s disease and diabetes mellitus. Lancet i (8235): 1420 1981.

  • 7. Arkkila PE Kantola IM Viikari JSRönnemaa T Vähätalo MA. Dupuytren's disease in type 1 diabetic patients: a five-year prospective study. Clin Exp Rheumatol 14: 59-65 1996.

  • 8. Dupuytren G. Permanent retraction of the fingers produced by an affection of the palmer fascia. Lancet 22: 222-225 1834.

  • 9. Melhorn JM Ackerman WE. Musculoskeletal disorders. In: Guides to the evaluation of disease and injury causation. Melhorn JM & Ackerman WE IIIrd (Eds). Am Med Assoc Press Chicago pp. 147-152; pp. 191-202 2007.

  • 10. Geraci A Bianchi R Sanfilippo AD’Arienzo M. Dupuytren contracture in diabetic hand. Endocrin Stud vol. 1:e2 pp. 6 2011.

  • 11. Jennings AM Milner PC Ward JD. Hand abnormalities are associated with the complications of diabetes in type 2 diabetes: Diabetic Med 6: 43-47

  • 1989.

  • 12. Gamstedt J Holm-Glad J Ohlson CGSundström M. Hand abnormalities are strongly associated with the duration of diabetes mellitus. JIntern Med 234: 189-193 1993.

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