Usefulness of the assessment of discharge accumulation in the lower airways and tracheal septum thickening in the differential diagnosis of recurrent airway obstruction (RAO) and inflammatory airway disease (IAD) in the horse

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Abstract

The aim of the present study was to use endoscopic evaluation to compare the grade of accumulation of discharge in the lower airways of horses with recurrent airway obstruction (RAO) and inflammatory airway disease (IAD), and to estimate the usefulness of endoscopic evaluation in differential diagnosis of these diseases. Endoscopic evaluation consists of: the amount of discharge in the lower part of the trachea and tracheal bifurcation, and the assessment of tracheal septum thickness. This study was performed on 248 horses, 10 were healthy, 97 were diagnosed as RAO, and 141 were diagnosed as IAD. In all animals both a clinical and endoscopic examination were performed. During endoscopy, a score of mucus accumulation was estimated in 3/4 lower of the trachea and in the tracheal bifurcation. In addition to this, thickening of the tracheal septum was also assessed. According to the results of this study, it was estimated that the accumulation of mucus in the lower airways was much more advanced in RAO horses compared to horses with IAD. In horses with RAO there was a marked thickening of the tracheal septum compared to IAD horses. The results indicate the efficacy of scoring the amount of mucus in the tracheal lumen and tracheal bifurcation, as well as the efficacy of the assessment of tracheal septum thickness in the diagnosis of these diseases

Allen K, Franklin S. (2007), RAO and IAD: respiratory disease in horses revisited. In Practice 29: 76-85.

Bartner LR, Robinson NE, Kiupel M, Tesfaigzi (2006) Persistent mucus accumulation: consequences of delayed bronchial mucous cell apoptosis in RAO affected horses? Am J Physiol Lung Cell Mol Phisiol 291: L602-609.

Beech J (1975) Cytology of tracheobronchial aspirates in horses Vet Pathol 12: 157-164.

Cardwell JM, Christley RM, Gerber V, Malkide N, Wood J LN, Newton R, Hodgson JL (2011) What’s in a name? Inflammatory airway disease in racehorses in training. Equine Vet J 43: 756-758.

Coue¨til LL, Hoffman AM., Hodgson J, Buechner - Maxwell V, Viel L, Wood JLN , Lavoie JP. (2007) Infalmmatory airway disease of horses. J Vet Intern Med 21: 356-361.

Derksen FJ, Brown CM, Sonea I, Darien BJ, Robinson NE. (1989) Comparison of transtracheal aspirate and bronchoalveolar lavage cytology in 50 horses with chronic lung disease. Equine Vet J 21: 23-26.

Gerber V, Baleri D, Klukowska-Rotzler J, Swinburne JE, Dolf G (2009) Mixed inheritance of equine recurrent airway obstruction. J Vet Intern Med. 23: 626-630.

Gerber V, Straub R, Marti E, Hauptman J, Herholz C, King M, Imhof A, Tahon L, Robinson NE (2004) Endoscopic scoring of mucus quantity and quality: observer and horse variance and relationship to inflammmation, mucus viscoelasticity and volume. Equine Vet J 36: 576-582.

Kluciński W, Winnicka A, Olszewski M, Sikora J, Sitarska E, Niemiałtowski M, Muzylak M, Bylinka G, Wyszyński M (1994 ) Phagocytic activity of polymorphonuclear leukocytes lavaged from the lungs of horses with clinically diagnosed chronic pulmonary disease. Zentralbl Veterinarmed A 41: 558-567.

Koblinger K, Nicol J, Mcdonald K Wasko A, Logie N, Weiss M, Le’guillette R (2011) Endoscopic assessment of airway inflammation in horses. J Vet Intern Med 25: 1118-1126.

Koch C, Straub R, Ramseyer A, Widmer A, Robinson NE, Gerber V (2007) Endoscopic scoring of the tracheal septum in horses and its clinical relevance for the evaluation of lower airway health in horses. Equine Vet J 39: 107-122.

Laus F, Attil AR, Cerquetella M, Spaterna B, Tesse B, Cuteri V (2009) Endoscopic findings, microbiological and cytological evaluation of tracheal aspirates in a population of standardbred horses with poor performances. Vet Med - Czech 54: 444-450.

Olszewski M, Kluciński W (1993), Chronic pulmonary disease in horse (COPD). Medycyna Wet. 49:70-73.

Whitweel KE, Greet TR, (1984) Collection and evaluation of tracheobronchial washes in the horse. Equine Vet J 16: 499-508.

Polish Journal of Veterinary Sciences

The Journal of Committee of Veterinary Sciences of Polish Academy of Sciences and University of Warmia and Mazury in Olsztyn

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