Atypical Heart Defect in One of the Twins with Trisomy 21

Open access

Abstract

Twin gestations are higher risk pregnancies for fetal mortality especially when associated with genetic disorder and congenital heart defect which significantly increases the complication risk in the co-twin including fetal loss, premature delivery, and organ damage. In this report, we present a case of dichorionic twins in 41 years old woman. A trisomy 21 was diagnosed in one twin associated with uncharacteristic congenital heart defect resulting in single twin demise in mid-gestation. The effect of regular care and proper management was delivery of healthy surviving twin.

1. Respondek-Liberska M., Nowicki G., Krasoń A., Kaczmarek P., Kociszewska I. i Danuta B., „Can we suspect fetal down syndrome by heart evaluation during the second half of pregnancy?”.Fetal Diagn Ther. 1999 May-Jun;14(3):143-8

2. Juchnowicz-Bierbasz Romuald, Szydłowski Lesław, Sysa Andrzej, Respondek-Liberska Maria. [Effectiveness of prenatal detection of heart defects in Down Syndrome based on bicenters maternal questionnaires]. Prenat Cardio. 2012 Sep;2(4):10-15. [Polish]

3. Mogra R., Zidere V.i Allan L., „Prenatally detectable congenital heart defects in fetuses with Down syndrome.”.Ultrasound Obstet Gynecol. 2011 Sep;38(3):320-4. doi: 10.1002/uog.8977. Epub 2011 Jul 7

4. Ville Y., „How to improve the screening and diagnosis of fetal aneuploidy?”.Bull Acad Nati Med. 2005, 189, 1773-1787

5. Respondek-Liberska M., Szymkiewicz-Dangel J., Tobota Z.i Słodki M., „Założenia i wstępne wnioski Ogólnopolskiego Rejestru Patologii Kardiologicznych Płodów (www.orpkp.pl).” .Pol Przegl Kardiol. 2008, 10, 129-135

6. Chaoui R., „Fetal echocardiography: state of the art of the state of the heart.”.Ultrasound Obstet Gynecol. 2001 Apr;17(4):277-84

7. Garne E., Stoll C., Clementil M.i The Euroscan Group, „Evaluation of prenatal diagnosis of congenital heart diseases by ultrasound: experience from 20 European registries”.Ultrasound Obstet Gynecol 2001; 17: 386-391

8. Tegnander E., Williams W., Johansen O., Blaas H.-G.i Eik-Nes S., „Prenatal detection of heart defects in a non-selected population of 30 149 fetuses - detection rates and outcome”.Ultrasound Obstet Gynecol 2006; 27: 252-265

9. Własienko P., Hamela-Olkowska A., Jalinik K. i Szymkiewicz- Dangel J., „Możliwość oceny płodowego układu krążenia pomiędzy 11,0 a 13,6 tygodniem ciąży w referencyjnym ośrodku kardiologii perinatalnej.”.Ginekol Pol. 2009, 80,268-273

10. Allan L., „Cardiac anatomy screening: what is the best time for screening in pregnancy?”.Curr Opin Obstet Gynecol. 2003 Apr;15(2):143-6

11. Allan L., „A practical approach to fetal heart scanning.”.Semin Perinatol. 2000 Oct;24(5):324-30

Journal Information

Metrics

All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 74 74 4
PDF Downloads 27 27 3