Synthesis of Some New Thiazolidine Derivatives and Their Biological Significance

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Synthesis of Some New Thiazolidine Derivatives and Their Biological Significance

An efficient route for the synthesis of new series of N-[3-(1H-1,2,3-benzotriazol-1-yl)-propyl]-2-(substituted phenyl)-4-oxo-5-(substituted benzylidene)-1,3-thiazolidine carboxamide, compounds 5 (a-j) has been elaborated. The compounds 5 (a-j) have been synthesized and characterized by IR, 1H NMR, 13C NMR, FAB Mass spectra and chemical analysis. All final compounds were screened for their antimicrobial activity against some selected bacteria, fungi, antituberculosis (against M. tuberculosis) and antiinflammatory activity on albino rats.

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Latvian Journal of Chemistry

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