Recent Advances in Role of Propolis as Natural Additive in Poultry Nutrition

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Propolis is a natural resinous mixture produced by honey bees from substances collected from parts of plants, buds and exudates. Due to its waxy nature and mechanical properties, bees use propolis in the construction and repair of their hives for sealing openings and cracks and smoothing out the internal walls and as a protective barrier against external invaders and weathering threats. Bees gather propolis from different plants, in the temperate climate zone mainly from poplar. About 300 compounds such as polyphenols, phenolic aldehydes, sequiterpene quinines, coumarins, amino acids, steroids and inorganic compounds have been identified in propolis samples. Several scientific studies have been focused on the biological activities of propolis and its functions as a health supplement in humans. It could have akin function in poultry. This review is focused on the current findings relating to chemical composition, as an antioxidant, on performance, immunity, intestinal flora and haematological parameter in domesticated poultry species (broiler chickens, laying hens, quail and duck).

Abbas, R.J. (2014). Effect of dietary supplementation with differing levels of propolis on productivity and blood parameters in broiler chicks. Basrah Journal of Veterinary Research, 13(2), 164-180.

Abd El-Hady, F.K. & Hegazi, A.G. (1994). Gas chromatography - mass spectrometry (GC/MS) study of the Egyptian propolis 1- aliphatic, phenolic acids and their esters. Egyptian Journal of Applied Sciences, 9, 749-760.

Abdel-Kareem, A.A.A. & El-Sheikh, T.M. (2015). Impact of supplementing diets with propolis on productive performance, egg quality traits and some haematological variables of laying hens. Journal of Animal Physiology and Animal Nutrition, 101(3), 441-448. DOI: 10.1111/jpn.12407

Abdel-Mohsein, H.S., Mahmoud, M.A.M. & Mahmoud, U.T. (2014). Influence of propolis on intestinal microflora of Ross broilers exposed to hot environment. Advances in Animal and Veterinary Sciences, 2(4), 204-211.

Abdel-Rahman, M.A. & Mosaad, G.M. (2013). Effect of propolis as additive on some behavioural patterns, performance and blood parameters in muscovy broiler ducks. Journal of Advanced Veterinary Research, 3, 64-68.

Abou-Zeid, A.E., El-Damarawy, S.Z., Mariey, Y.A. & El- Kasass, S.M. (2015). Effect of dietary propolis supplementation on performance and activity of antioxidant enzymes in broiler chickens. Egyptian Journal of Nutrition and Feeds, 18, 391- 400.

Açikgöz, Z., Yücel, B. & Altan, O. (2005). The effects of propolis supplementation on broiler performance and feed digestibility. Archiv Fur Geflugelkunde, 69S, Ahn, M.R., Kumazawa, S., Hamasak, T., Bang, K.S., Nakayama, T. (2004). Antioxidant activity and constituents of propolis collected in various areas of Korea.

Journal of Agricultural and Food Chemistry, 52, 7286-7292. DOI: 10.1021/jf048726s

Arslan, A.S. & Seven, P.T. (2017). The effects of propolis on serum malondialdehyde, fatty acids and some blood parameters in Japanese quail (Coturnix coturnix japonica) under high stocking density. Journal of Applied Animal Research, 45, 417-422.

Attia, Y.A., Abdal-Hamid, A.E., Ibrahim, M.S., Al-Harthi, M.A., Bovera, F., Elnaggar, A.S. (2014). Productive performance, biochemical and hematological traits of broiler chickens supplemented with propolis, bee pollen, and mannan oligosaccharides continuously or intermittently. Livestock Science, 164, 87-95.

Babaei, S., Rahimi, S., Torshizi, M.A.K, Tahmasebi, G., Miran, S.N.K. (2016). Effects of propolis, royal jelly, honey and bee pollen on growth performance and immune system of Japanese quails. Veterinary Research Forum, 7(1), 13-20.

Babińska, I., Kleczek, K., Makowski, W. & Szarek, J. (2013). Effect of feed supplementation with propolis on liver and kidney morphology in broiler chickens. Pakistan Vet Journal, 33(1), 1-4.

Basnet, P., Matsuno, T. & Neidlein, R. (1997). Potent free radical scavenging activity of propol isolated from Brazilian propolis. Zeitschrift für Naturforschung, 52C, 828-833.

Banskota, A.H., Tezuka, T., Adyana, I.K., Midorikawa, K., Matsushige, K., Message, D., … Kadota, S. (2000). Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China. Journal of Ethnopharmacology, 72(1-2), 239-246.

Belloni, M, Almeida, P.I.C.L., Nääs, I.A., Alves, M.C.F., Garcia, R.G., Caldara, F.R., Seno, L.O. (2015). Productive, qualitative, and physiological aspects of layer hens fed with propolis. Brazilian Journal of Poultry Science, 17(4), 467-472.

Bobko, M., Kročko, M., Haščík, P. & Bobková, A. (2015). Oxidative stability of chicken meat after propolis extract application in their diets. Potravinarstvo, 9, 48-52.

Bogdan, C. (2001). Nitric oxide and the immune response. Nature Immunology, New York, 2, 907-916.

Bonomi, A., Bonomi, B.M., Quarantelli, A., Sabbioni, A., Superchi, P. (2002). The use of propolis in duck feeding. Rivista di Scienza dell’Alimentazione, 31, 15-28.

Cantarelli, M.A., Caminia, J.M., Pettenati, E.M., Marchevsky, E.J., Pellerano, R.G. (2011). Trace mineral content of Argentinean raw propolis by neutron activation analysis (NAA): Assessment of geographical provenance by chemometrics. LWT-Food Science and Technology, 44, 256-260.

Çetin, E., Silici, S., Çetin, N. & Guclu, B.K. (2010). Effects of diets containing different concentrations of propolis on hematological and immunological variables in laying hens. Poultry Science, 89(8), 1703-1708.

Chen, S., Qiu, Z. & Lin, W. (1999). The immunogenicity of ultrasonicated vaccine of chicken pathogenic E. Coli (078) against Colibacillosis. Journal of South China Agricultural University, 20(1), 37-40.

Chen, C.N., Weng, M.S., Wu, C.L. & Lin, J.K. (2004). Comparison of radical scavenging activity, cytotoxic effects and apoptosis induction in human melanoma cells by Taiwanese propolis from different sources. Evidence-Based Complementary Alternative Medicine, 1:175-185. DOI: 10.1093/ecam/neh034

Cvek, J., Medid-Saric, M., Vitali, D., Vedrina-Dragojevik, I., Smit, Z., Tomic, S. (2008). The content of essential and toxic elements in Croatian propolis samples and their tinctures. Journal of Apicultural Research, 47, 35-45.

Da Silva, J.F.M., Souza, M.C., Matta, S.R., Andrade, M.R., Vidal, F.V.N. (2006). Correlation analysis between phenolic levels of Brazilian propolis extracts and their antimicrobial and antioxidant activities. Food Chemistry, 99(3), 431-435.

DaSilvaFrozza, C.O., Garcia, C.S.C., Gambato, G., de Souza, M.D.O., Salvador, M., Moura, S., Padilha, F.F., Seixa, F.K., Collares, T., Borsuk, S., Dellagostin, O.A., Henricues, J.A.P. & Roesch-Ely, M. (2013). Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis. Food and Chemistry Toxicology, 52,137-142.

De Castro, S.L. (2001). Propolis: Biological and pharmacological activities. Therapeutic uses of this beeproduct. Annual Review of Biomedical Sciences, 3, 49-83.

Denli, M., Cankaya, S., Silici, S., Okan, F., Uluocak, A.N. (2005). Effect of dietary addition of Turkish propolis on the growth performance, carcass characteristics and serum variables of quail (Coturnix coturnix japonica). Asian-Australasian Journal of Animal Science, 18(6), 848-854.

Dimov, V., Ivanoska, N., Manolova, N., Bankova, V., Nikolav, N., Popov, S. (1991). Immunomodulatory action of propolis. Influence on antiinfectious protection and macrophage function. Apidologie (Celle), 22(2), 155-162.

Drago, L., Mombelli, B., De Vecchi, E., Fassina, M.C., Tocalli, L., Gismondo, M.R. (2000). In-vitro antimicrobial activity of propolis dry extract. Journal of Chemotherapy, 12, 390-395.

El-Neney, B.A. & Awadien, N.B. (2014). The use of propolis as a source of natural additives to improve the productive performance and immune system of chickens local.1- effect on laying hen performance. 7th International Poultry Conference-Proceedings, organized by Animal Production Research Institute (APRI), Ain Sukhna, Egypt. pp, 58-78.

Eroglu, N., Senem, A., Mustafa, Y., Baris, A., Sibel, S. (2016). Amino acid and vitamin content of propolis collected by native caucasican honeybees. Journal of Apicultural Science, 60(2), 101-109.

Eyng, C., Murakami, A.E. & Pedroso, R.B. (2013). Crude propolis as an immunostimulating agent in broiler feed during the starter phase. Semina: Ciências Agrárias, Londrina, 34(5), 2511-2522.

Eyng, C., Murakami, A.E., Santos, T.C., Silveira, T.G.V., Pedroso, R.B., Lourenco, D.A.L. (2015). Immune responses in broiler chicks fed propolis extraction residue-supplemented diets. Asian-Australasian Journal of Animal Science, 28(1), 135-142.

Freitas, J.A., Vanat, N., Pinheiro, J.W., Balarin, M.R.S., Sforcin, J.M., Venancio, E.J. (2011). The Effects of propolis on antibody production by laying hens. Poultry Science, 90, 1227-1233.

Galal, A., Abd El-Motaal, A.M., Ahmed, A.M.H., Zaki, T.G. (2008). Productive performance and immune response of laying hens as affected by dietary propolis supplementation. International Journal of Poultry Science, 7(3), 272-278.

Gómez-Caravaca, A., Gómez-Romero, M., Arráez-Román, D., Segura-Carretero, A., Fernández-Gutiérrez, A. (2006). Advances in the analysis of phenolic compounds in products derived from bees. Journal of Pharmaceutical and Biomedical Analysis, 41, 1220-1234.

Haščik, P., Garlik, J., Elimam, I.O.E., Kňazovicka, V., Bobko, M., Kačaniova, M. (2014). Influence of propolis extract in Hubbard JV chickens nutrition on oxidative stability of meat. Acta Fytotechnica et Zootech, 17(2), 47-51. DOI: 10.15414/afz.2014.17.02.47-51

Haščík, P., Trembecká, L., Bobko, M., Kačániová, M., Čuboň, J., Kunová, S., Bučk, O. (2016). Effect of diet supplemented with propolis extract and probiotic additives on performance, carcass characteristics and meat composition of broiler chickens. Potravinarstvo, 10(1), 223-231. DOI: 10.5219/581

Hassan, M.G. & Abdulla, T.A.(2011). The effect of propolis feed supplementation on hygiene and performance of broiler chickens. Iraqi Journal of Veterinary Science, 25(2), 77-82.

Havsteen, B.H. (2002). The biochemistry and medical significance of the flavonoids. Pharmacology & Therapeutics, 96(2-3), 67-202.

Hegazi, A.G., El-Miniawy, H.F. & El-Miniawy, F.A. (1995). Effect of some honeybee products on immune response of chicken infected with Virulent NDV. Egyptian Journal of Immunology, 2(2), 79-86.

Hegazi, A., Abdou, A.M. & Allah, F.A. (2012). Egyptian propolis 9- Its effect on chicken productivity and immune response against Newcastle disease vaccine. British Journal of Poultry Science, 1(3), 25-30. DOI: 10.5829/idosi.bjps.2012.1.3.8147

Hosnuter, M., Gurel, A., Babuccu, O., Armutcu, F., Kargi, E., Isikdemir, A. (2004). The effect of CAPE on lipid peroxidation and nitric oxide levels in the plasma of rats following thermal injury. Burns, 30, 121-125.

Hosseini, S.M., Vakili Azghandi, M., Ahani, S., Nourmohammadi, R. (2016). Effect of bee pollen and propolis (bee glue) on growth performance and biomarkers of heat stress in broiler chickens reared under high ambient temperature. Journal of Animal and Feed Sciences, 25(1), 45-51. file:///C:/Users/sohail/Downloads/6_hosseini.pdf

Huang, W.J., Huang, C.H., Wu, C.L., Lin, J.K., Chen, Y.W., Lin, C.L., Chuang, S.E., Huang, C.Y., Chen, C.N. (2007). Propolin G, a prenylflavanone, isolated from Taiwanese propolis, induces caspase-dependent apoptosis in brain cancer cells. Journal of Agricultural and Food Chemistry, 55(18), 7366-76. DOI: 10.1021/jf0710579

Huang, S., Cui-Ping, Z., Kai, W., George, Q.L., Fu-Liang, H. (2014). Recent advances in the chemical composition of propolis. Molecules. 19, 19610-19632. DOI: 10.3390/molecules191219610

Kačániová, M., Haščík, P., Arpášová, H., Pavelková, A., Petrová, J., Hleba, L., Pochop, J., Rovná, K. (2013). Enterococcus genus identification isolated from gastrointestinal tract of chickens after bees products application using MALDI TOF MS Biotyper. Animal Science and Biotechnology, 46, 114-118. file:///C:/Users/sohail/Downloads/172-1403-1-PB%20(1).pdf

Kačániová, M., Rovná, K., Arpášová, H., Cuboň, J., Hleba, L., Pochop, J., Kunová, S., Haščík, P. (2012). In vitro and in vivo antimicrobial activity of propolis on the microbiota from gastrointestinal tract of chickens. Journal of Environmental Science and Health Part A Toxic/Hazardous Substances & Environmental Engineering, 47(11), 1665-1671. DOI: 10.1080/10934529.2012.687248

Kleczek, K., Majewska, K., Makowski, W., Michalik, D. (2012). The effect of diet supplementation with propolis and bee pollen on the physicochemical properties and strength of tibial bones in broiler chickens. Archiv Tierzucht, 55, 97-103.

Kleczek, K., Wilkiewicz-Wawro, E., Wawro, K., Makowski, W., Murawska, D., Wawro, M. (2014). The effect of dietary propolis supplementation on the growth performance of broiler chickens. Polish Journal of Natural Sciences, 29(2), 105-117.

Kosalec, I., Bakmaz, M., Pepeljnjak, S., & Vladimir-Knezevic, S. (2004). Quantitative analysis of the flavonoids in raw propolis from northern Croatia. Acta Pharmacology, 54, 65-72. file:///C:/Users/sohail/Downloads/6504.pdf

Kumar, S. & Pandey, A.K. (2013). Chemistry and Biological Activities of Flavonoids: An Overview. The Scientific World Journal, 2013. Article ID: 162750.

Kumazawa, S., Hamasaka, T. & Nakayama, T. (2004). Antioxidant activity of propolis of various geographic origins. Food Chemistry, 84(3), 329-339.

Kurek-Górecka, A., Rzepecka-Stojko, A., Górecki, M., Stojko, J., Sosada, M., Swierczek-Zieba, G. (2014). Structure and antioxidant activity of polyphenols derived from propolis. Molecules, 19(1), 78-101. DOI: 10.3390/molecules19010078

Lan, Y., Verstegen, M.W.A., Tamminga, S. & Williams, B.A. (2005). The role of the commensal gut microbial community in broiler chickens. World’s Poultry Science Journal, 61(1), 95-104. DOI:

Li, Z. & Zhang, Z. (2002). Effects of ration supplemented with propolis on live weight gain of broilers. China Poultry, 24, 22.

Lotfy, M. (2006). Biological activity of bee propolis in health and disease. Asian Pacific Journal of Cancer Prevention, 7(1), 22-31.

Lu, J., Idris, U., Harmon, B., Hofacre, C., Maurer, J.J., Lee, M.D. (2003). Diversity and succession of the intestinal bacterial community of the maturing broiler chicken. Applied and Environmental Microbiology, 69(11), 6816-6824. DOI: 10.1128/AEM.69.11.6816-6824.2003

Mahmoud, M.A.M., Abdel-Mohsein, H.S. & Mahmoud, U.T. (2014). Effect of Chinese propolis supplementation on Ross broiler chicks: microbial population in fecal matter and litter. Journal of Advanced Veterinary Research, 4(2), 77-84.

Mahmoud, U.T., Abdel-Rahman, M.A. & Darwish, M.H.A. (2013). The effect of Chinese propolis supplementation on Ross broiler performance and carcass characteristics. Journal of Advanced Veterinary Research, 3(4), 154-160.

Mahmoud, M.A.M., Abdel-Rahman, M.A. & Farghali, M.R.F. (2015). Antioxidant properties of Chinese propolis in Ross broilers exposed to heat stress in Egypt. Open Journal of Veterinary Medicine, 5, 197-209.

Marieke, M., Blitterswijk, H., Leven, L., Kerkvliet, J., Waerd, J. (2005). Bee products (properties, processing and marketing). Agrodok 42, NECTAR, Netherlands Expertise Centre for (sub) Tropical Apicultural Resources, pp, 33-35.

Martinez-Tome, M., Jiménez, A.M., Ruggieri, S., Frega, N., Strabbioli, R., Murcia, M.A. (2001). Antioxidant properties of Mediterranean spices compared with common food additives. Journal of Food Protection, 64(9), 1412-1419.

Matsui, T., Ebuchi, S., Fujise, T., Abesundara, K.J., Doi, S., Yamada, H., Matsumoto, K. (2004). Strong antihyperglycemic effects of water-soluble fraction of Brazilian propolis and its bioactive constituent, 3,4,5-tri-O-caffeoylquinic acid. Biological and Pharmaceutical Bulletin, 27(11), 1797-1803.

Miguel, M.G. & Antunes, M.D. (2011). Is propolis safe as an alternative medicine? Journal of Pharmacy and Bioallied Sciences, 3(4), 479-495. DOI: 10.4103/0975-7406.90101

Mishra, A., Kumar, S. & Pandey, A.K. (2013). Scientific validation of the medicinal efficacy of Tinospora cordifolia. The Scientific World Journal, Article ID: 292934.

Moreira, T.F. (1986). Chemical composition of propolis: Vitamins and amino acids. Revista Brasileira de Farmacognosia, 1(1), 12-19.

Nakajima, Y., Shimazawa, M., Mishima, S. & Hara, H. (2007). Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions. Life Sciences, 80(4), 370-377. DOI: 10.1016/j. lfs.2006.09.017

Nimse, S.B. & Pal, D. (2015). Free radicals, natural antioxidants, and their reaction mechanisms. Royal Society of Chemistry Advances, 5, 27986-28006. DOI: 10.1039/C4RA13315C

Ozkok, D., Iscan, K.M. & Ilici, S. (2013). Effects of dietary propolis supplementation on performance and egg quality in laying hens. Journal of Animal and Veterinary Advances, 12(2), 269-275. DOI: 10.3923/javaa.2013.269.275

Orsi, R.O., Funari, S.R.C., Soares, A.M.V.C., Calvi, S.A., Oliveira, S.L., Sforcin, J.M., Bankova, V. (2000). Immunomodulatory action of propolis on macrophage activation. Journal of Venomous Animals and Toxins Including Tropical Diseases, 6, 205-219.

Park, Y.K., Alencar, S.M. & Aguiar, C.L. (2002). Botanical origin and chemical composition of Brazilian propolis. Journal of Agricultural and Food Chemistry, 50(9), 2502-2506. DOI: 10.1021/jf011432b

Park, J.H., Lee, J.K., Kim, H.S., Chung, S.T., Eom, J.H., Kim, K.A., … Oh, S.U. (2004). Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice. International Immunopharmacology, 4(3), 429-436. DOI: 10.1016/j.intimp.2004.01.013

Pavilonis, A., Baranauskas, A., Puidokaite, L., Mazeliene, Z., Savickas, A., Radziūnas, R. (2008). Antimicrobial activity of soft and purified propolis extracts. Medicina (Kaunas, Lithuania), 44(12), 977-983. PMID:19142056

Peric, I., Zikie, D. & Lukie, M. (2009). Application of alternative growth promoters in broiler production. Biotechnology in Animal Husbandry, 25(5-6), 387-397.

Popova, M.P., Graikou, K., Chinou, I. & Bankova, V.S. (2010). GC-MS profiling of diterpene compounds in Mediterranean propolis from Greece. Journal of Agricultural and Food Chemistry, 58(5), 3167-3176. DOI: 10.1021/jf903841k

Popova, M., Trusheva, B., Cutajar, S., Antonova, D., Mifsud, D., Farrugia, C., Bankova V. (2012). Identification of the plant origin of the botanical biomarkers of Mediterranean type propolis. Natural Product Communications, 7(5), 569-570.

Roodsari, M.H., Mehdizadeh, M., Kasmani, F.B., Lotfelahian, H., Mosavi, F., Abolghasemi, A.H. (2004). Effects of oil-extracted propolis on the performance of broiler chicks. Agricultural Science and Technology, 18, 57-65.

Salatino, A., Erica, W.T., Giuseppina, N. & Dejair, M. (2005). Origin and chemical variation of Brazilian propolis. Evidenced-Base Compliment and Alternative Medicine, 2(1): 33-38. DOI: 10.1093/ecam/neh060

Sathiavelu, J., Senapathy, G.J., Devara, R., & Namasivayam, N. (2009). Hepatoprotective effect on chrysin on prooxidant-antioxidant status during ethanol-induced toxicity in female albino rats. Journal of Pharmacy and Pharmacology, 61(6), 809-817. DOI: 10.1211/jpp.61.06.0015

Scheller, S., Dworniczak, S., Waldemar-Klimmek, K., Rajca, M., Tomczyk, A., Shani, J. (1999). Synergism between ethanolic extract of propolis and antituberculosis drugs on growth of mycobacteria. Zeitschrift für Naturforschung, 54(7-8), 549-553. PMID:10488563

Schnitzler, P., Neuner, A., Nolkemper, S., Zundel, C., Nowack, H., Sehsch, K.H., Reichling, J. (2010). Antiviral activity and mode of action of propolis extracts and selected compounds. Phytotherapy Research, 24(1), S20-S28. DOI: 10.1002/ptr.2868

Simone-Finstrom, M. & Spivak, M. (2010). Propolis and bee health: the natural history and significance of resin use by honey bees. Apidologie, 41(3), 295-311. DOI: 10.1051/apido/2010016

Seven, P.T. (2008). The Effects of dietary Turkish propolis and vitamin C on performance, digestibility, egg production and egg quality in laying hens under different environmental temperatures. Asian-Australasian Journal of Animal Sciences, 21(8), 1164 -1170. DOI:

Seven, P.T. & Seven, I. (2008). Effect of dietary Turkish propolis as alternative to antibiotic on performance and digestibility in broilers exposed to heat stress. Journal of Applied Animal Research, 34(2), 193-196.

Seven, T.P, Seven, I., Yilmaz, M. & Simsek, U.G. (2008). The effects of Turkish propolis on growth and carcass characteristics in broilers under heat stress. Animal Feed Science and Technology, 146(1-2), 137-148.

Seven, P.T., Yilmaz, S., Seven, I., Cerci, I.H., Azman, A., Yilmaz, M. (2009). Effects of propolis on selected blood indicators and antioxidant enzyme activities in broilers under heat stress. Acta Veterinaria Brno, 78(1), 75-83.

Seven, I., Aksu, T. & Tatli, S.P. (2010). The effects of propolis on biochemical parameters and activity of antioxidant enzymes in broiler exposed to lead induced oxidative stress. Asian-Australasian Journal of Animal Sciences, 23(11), 1482-1489. DOI:

Seven, I., Tatli, S.P. & Silici, S. (2011). Effects of dietary Turkish propolis as alternative to antibiotic on growth and laying performances, nutrient digestibility and egg quality in laying hens under heat stress. Revue de Médecine Vétérinaire, 162(4), 186-191.

Seven, I., Aksu, T. & Tatli, S.P. (2012a). The effects of propolis and vitamin c supplemented feed on performance, nutrient utilization and carcass characteristics in broilers exposed to lead. Livestock Science, 148(1-2), 10-15.

Seven, P.T., Yilmaz, S., Seven, I. & Tuna, K.G. (2012b). The Effects of Propolis in Animals Exposed Oxidative Stress. In: Lushchak, V.I., Ed., Oxidative Stress- Environmental Induction and Dietary Antioxidants, Chap. 13, InTech Book, Rijeka, 267-288.

Sforcin, J.M. (2007). Propolis and the immune system: a review. Journal of Ethnopharmacology, 113(1), 1-14. DOI: 10.1016/j.jep.2007.05.012

Shaddel-Tili, A., Eshratkhah, B., Kouzehgari, H. & Ghasemi-Sadabadi, M. (2016). The effect of different levels of propolis in diets on performance, gastrointestinal morphology and some blood parameters in broiler chickens. Bulgarian Journal of Veterinary Medicine, DOI: 10.15547/bjvm.986

Shalmany, S.K. & Shivazad, M. (2006). The effect of diet propolis supplementation on Ross broiler chicks performance. International Journal of Poultry Science, 5(1), 84-88.

Shihab, I.M., & Ali, B.H. (2012). Effect of propolis in diet supplementation on the immune response against Newcastle disease and hematological picture in broiler chicks. Al-Anbar Journal of Veterinary Sciences, 5(2), 40-46.

Silici, S. & Kutluca, S. (2005). Chemical composition and antibacterial activity of propolis collected by three different races of honeybees in the same region. Journal of Ethnopharmacology, 99(1), 69-73. DOI: 10.1016/j.jep.2005.01.046

Szliszka, E., Kucharska, A.Z., Sokol-Letowska, A., Mertas, A., Czuba, Z.P., Krol, W. (2013). Chemical composition and anti-inflammatory effect of ethanolic extract of Brazilian green propolis on activated J774A.1 Macrophages. Evidence-Based Complement Alternative Medicine, Article ID 976415.

Taheri, H.R., Rahmani, H.R. & Pourreza, J. (2005). Hu moral immunity of broilers is affected by oil extracted propolis (OEP) in the diet. International Journal of Poultry Science, 4(6), 414-417.

Tayeb, I.T. & Sulaiman, B.F. (2014). Effect of propolis supplementation on productive performance in local quail. Iranian Journal of Applied Animal Science, 4(3), 621-627.

Tekeli, A., Kutlu, H.R., Celik, L. & Doran, F. (2010). Determination of the effects of Z. officinale and propolis extracts on intestinal microbiology and histological characteristics in broilers. International Journal of Poultry Science, 9(9), 898-906.

Tekeli, A., Kutlu, H.R. & Çelik, L. (2011). Effects of Z. officinale and propolis extracts on the performance carcass and some blood parameters of broiler chicks. Current Research Poultry Science, 1(1): 12-23.

Trusheva, B., Popova, M., Bankova, V., Simova, S., Marcucci, M.C., Miorin, P.L., Iva, T. (2006). Bioactive constituents of Brazilian red propolis. Evidence-Based Complementary and Alternative Medicine, 3(2), 249-254. DOI: 10.1093/ecam/nel006

Vynograd, N., Vynograd, I. & Sosnowski, Z. (2000). A comparative multicentre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV). Phytomedicine, 7(1), 1-6. DOI: 10.1016/S0944-7113(00)80014-8

Wagh, V.D. (2013). Propolis: A wonder bees product and its pharmacological potentials. Advances in Pharmacological Sciences, Article ID: 308249.

Wang, D., Li, X., Xu, L., Hu, Y., Zhang, B., Liu, J. (2006). Immunologic synergism with IL-2 and effects of cCHMIs on mRNA expression of IL-2 and IFN-γ in chicken peripheral T lymphocyte. Vaccine, 24(49-50), 7109-7114.

Yamauchi, R., Kato, K., Oida, S., Kanaeda, J., Ueno, Y. (1992). Benzyl caffeate, an antioxidative compound isolated from propolis. Bioscience, Biotechnology and Biochemistry, 56(8), 1321-1322.

Zafarnejad, K., Nazar, A. & Mostafa, R. (2017). Effect of bee glue on growth performance and immune response of broiler chickens. Journal of Applied Animal Research, 459(1), 280-284.

Zeng, Z., Liu, S., Pan, K., Wu, H., Tang, K. (2004). Effects of pollen and propolis on productive and immune performance in meat fowl. Scientia Agricultura Sinica, 37(5), 751-755.

Zeweil, H.S., Zahran, S.M., Abd El-Rahman, M.H.A., Dosoky, W.M., Abu Hafsa, S.H., Moktar, A.A. (2016). Effect of using bee propolis as natural supplement on productive and physiological performance of Japanese quail. Egyptian Poultry Science Journal, 36(1), 161-175.

Zhi-Jiang, Z., San-Feng, L., Ke, P., Hong-Xiang, W., Kai-Jie, T. (2004). Effects of pollen and propolis on productive and immune performance in meat fowl. Scientia Agriculura Sinica. 37: 751-755.

Ziaran, H.R., Rahmani, H.R. & Pourreza, J. (2005). Effect of dietary oil extract of propolis on immune response and broiler performance. Pakistan Journal of Biological Sciences, 8(10), 1485-1490.

Journal of Apicultural Science

The Journal of Research Institute of Horticulture and Apicultural Research Association

Journal Information

IMPACT FACTOR 2017: 0.75
5-year IMPACT FACTOR: 1.007

CiteScore 2017: 0.92

SCImago Journal Rank (SJR) 2017: 0.345
Source Normalized Impact per Paper (SNIP) 2017: 0.461


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