Content of 5-hydroxymethyl-2-furfural in biscuits for kids

Open access

Abstract

5-hydroxymethyl-2-furfural (5-HMF) is a thermal decomposition product of saccharides. There are two main ways for the formation of 5-HMF. First, 5-HMF is forming during Maillard reaction and second, during thermic dehydration of saccharides under acid conditions. Significant parameters of 5-HMF formation are temperature, time, pH, water activity, type of saccharide and amino acids. It is suspected that 5-HMF has genotoxic, mutagenic and carcinogenic potential. This chemical can be found in many food sources, e.g. honey, dried fruits, fruit juice and concentrates, alcoholic beverages, bakery products, roasted nuts and seeds, brown sugar, and milk. The present study aimed to determine the amount of 5-HMF in children's biscuits. The examined samples were divided into three groups. The first group of biscuits claimed availability for children older than six months, the second for children older than one year. The third group did not give a determined age range.

For the assessment of 5-HMF, a HPLC method with UV/VIS detection was used. In the first group of samples, the amount of 5-HMF ranged from 0.34±0.04 to 1.73±0.03 mg/kg, in the second group from 0.57±0.09 to 1.78±0.07 mg/kg, and in the third group the amounts of 5-HMF were from 1.80±0.05 to 34.99±0.22 mg/kg.

In conclusion, the results showed that the content of 5-HMF in biscuits without age group determination was significantly higher than in biscuits with declared availability for children older than six months or one year. Since the acceptable daily intake is 2 mg/kg bw, the established amount of 5-HMF in all samples cannot be regarded as dangerous in a normal dose of biscuits.

Ait-Ameur L, Trystram G, Birlouez-Aragon I. (2006). Accumulation of 5-hydroxymethyl-2-furfural in cookies during the backing process: Validation of an extraction method. Food Chemistry 98(4): 790–796.

Arribas-Lorenzo G, Morales FJ. (2010). Estimation of dietary intake of 5-hydroxymethylfurfual and related substances from coffee to Spanish population. Food Chem Toxicol 48(2): 644–649.

Capuano E, Fogliano V. (2011). Acrylamide and 5-hydroxymethylfurfural (HMF): A review on metabolism, toxicity, occurence in food and mitigation strategies. LWT - Food Sci Tech 44 (4): 793–810.

Delgado-Andrade C, Seiquer I, Navarro MP, Morales FJ. (2008). Estimation of hydroxymethylfurfural availability in breakfast cereals. Studies in Caco-2 cells. Food Chem Toxicol 46(5): 1600–1607.

Delgado-Andrade C, Rufián-Henares JA, Morales FJ. (2009). Hydroxymethylfurfural in commercial biscuits marketed in Spain. J Food Nutrition Res 48(1): 14–19.

Gökmen V, Acar J. (1999). Simultaneous determination of 5-hydroxymethylfurfural and patulin in apple juice by reversed-phase liquid chromatography. J Chromatogr A 847(1–2): 69–74.

Janzowski C, Glaab V, Samimi E, Schlatter J, Eisenbrand G. (2000). 5-hydroxymethylfurfural : assesment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione. Food Chem Toxicol 38: 801–809.

Kowalski S, Lukasiewicz M, Duda-Chodak A, Zięć G. (2013). 5-Hydroxymethyl-2-furfural (HMF)-heat-induced formation, occurence in food and biotransfromation – a Review. Polish Journal of Food and Nutrition Science 63(4): 207–225.

Lee TP, Sakai R, Manaf NA, Rodhi AM, Saad B. (2014). High perfomance liquid chromatography method for the determination of patulin and 5-hydroxymthylfurfural in fruit juices marketed in Malaysia. Food Control 38: 142–149.

Nguyen HT, Van der Fels-Klerx HJ (Ine), Peters RJB, Van Boekel MAJS. (2016). Acrylamide and 5-hydroxymethylfurfural formation during baking of biscuits: Part I: Effects of sugar type. Food Chemistry 192: 575–585.

Petisca C, Henriques AR, Pérez-Palacios T, Pinho O, Ferreira IMPLVO. (2014). Assesment of hydroxymethylfurfural and furfural in commercial bakery products. J Food Compos Anal 33(1): 20–25.

Polovková M, Simko P. (2017) Determination and occurrence of 5-hydroxymethyl-2-furfuraldehyde in white and brown sugar by high perfomance liquid chromatography. Food Control 78: 183–186.

Rada-Mendoza M, Olano A, Villamiel M. (2002). Determination of hydroxymthylfurfural in commercial jams and in fruit-based infant foods. Food Chemistry 79(4): 513–516.

Ramírez-Jiménez A, García-Villanova B, Guerra-Hernández E. (2000). Hydroxymethylfurfural and methylfurfural content of selected bakery products. Food Res Int 33(10): 833–838.

Sacchetti G, Iannone F, De Gregorio M, Di Mattia C, Serafini M, Mastrocola D. (2016). Non enzymatic browning during coca roasting as affected by processing time and temperature. J Food Eng 169: 44–52.

Van der Fels-Klerx HJ, Capuano E, Nguyen HT, Ataç Mogol B, Kocadağli T, Göncüoğlu Taş N, Hamzalioğlu A., Van Boekel M.A.J.S., Gökmen V. (2014). Acrylamide and 5-hydroxymethylfurfural formation during baking of biscuits : NaCl and temperature-time profile effects and kinetics. Food Res Int 57: 210–217.

Interdisciplinary Toxicology

The Journal of Institute of Experimental Pharmacology of Slovak Academy of Sciences

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CiteScore 2018: 1.78

SCImago Journal Rank (SJR) 2018: 0.274
Source Normalized Impact per Paper (SNIP) 2018: 0.671

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