Regulatory T cells (Treg cells) are a group of negative regulatory cells that include non-specific immune regulation CD4+ T cells. Treg cells inhibit the function of other immune cells. CD4+ CD25+ FOXP3+ is a Treg cell that is co-expressed by CD25 and FOXP3. The expression of Treg cells is up-regulated in the focal microenvironment and peripheral blood of patients infected with human papilloma virus (HPV). Further studies on Treg cells indicate that their potential clinical applications in the treatment of HPV infection.
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