Chinese Consensus on Diagnosis and Treatment of Hepatic Encephalopathy

Chinese Expert Committee on Hepatic Encephalopathy

  • 1 Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University; 8 East Jingshun Street, Chaoyang District, , Beijing, China

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  • 1. Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, Blei AT. Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11thWorld Congresses of Gastroenterology, Vienna, 1998. Hepatology 2002;35:716-721.

  • 2. Blei AT, Cordoba J. Hepatic Encephalopathy. Am J Gastroenterol 2001;96:1968-1976.

  • 3. Riordan SM, Williams R. Treatment of hepatic encephalopathy. N Engl J Med 1997;337:473-479.

  • 4. Zhu CW, Zhu WN. Hepatic encephalopathy. Practice of internal medicine. Beijing:People Medical Press. 2007;2026-2033.

  • 5. Hassanein TI, Hilsabeck RC, Perry W. Introduction to the Hepatic Encephalopathy Scoring Algorithm (HESA). Dig Dis Sci 2008;53:529-538.

  • 6. Fu YZ, Xie JW. The application of clock drawing test and MMSE in diagnosis of minimal hepatic encephalopathy. J Clin Res 2007;8:1280-1282.

  • 7. Romero-Gomez M, Cordoba J, Jover R, del Olmo JA, Ramirez M, Rey R, et al. Value of the critical flicker frequency in patients with minimal hepatic encephalopathy. Hepatology 2007;45:879-885.

  • 8. Cordoba J, Lopez-Hellin J, Planas M, Sabin P, Sanpedro F, Castro F, et al. Normal protein diet for episodic hepatic encephalopathy: results of a randomized study. J Hepatol 2004;41:38-43.

  • 9. Plauth M, Cabre E, Riggio O, Assis-Camilo M, Pirlich M, Kondrup J, et al. ESPEN Guidelines on Enteral Nutrition: Liver disease. Clin Nutr 2006;25:285-294.

  • 10 Shi H, Liu HY. Diagnosis of hepatic encephalopathy. Jia L, Li ZS. Chief editors. Hepatic Encephalopathy, Beijing, People’s Military Medical press.2007:94-105.

  • 11. Morgan MY, Blei A, Grungreiff K, Jalan R, Kircheis G, Marchesini G, et al. The treatment of hepatic encephalopathy. Metab Brain Dis 2007;22:389-405.

  • 12. Prasad S, Dhiman RK, Duseja A, Chawla YK, Sharma A, Agarwal R. Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy. Hepatology 2007;45:549-559.

  • 13. Als-Nielsen B, Gluud LL, Gluud C. Nonabsorbable disaccharides for hepatic encephalopathy. Cochrane Database Syst Rev 2004;2:CD003044.

  • 14. Sharma P, Sharma BC, Puri V, Sarin SK. An open-label randomized controlled trial of lactulose and probiotics in the treatment of minimal hepatic encephalopathy. Eur J Gastroenterol Hepatol 2008;20:506-511.

  • 15. Al Sibae MR, McGuire BM. Current trends in the treatment of hepatic encephalopathy. Ther Clin Risk Manag 2009;5:617-626.

  • 16. Bass N, Mullen K, Sigal S, Sanyal A, Poordad F, Merchant K, et al. Rifaximin is effective in maintaining remission in hepatic encephalopathy: Results of a large, randomized, placebocontrolled trial. J Hepatol 2009;50 (Suppl 1):S53.

  • 17. Mas A, Rodes J, Sunyer L, Rodrigo L, Planas R, Vargas V, et al. Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial. J Hepatol 2003;38:51-58.

  • 18. Jiang Q, Jiang XH, Zheng MH, Jiang LM, Chen YP, Wang L. Rifaximin versus nonabsorbable disaccharides in the management of hepatic encephalopathy: a meta-analysis. Eur J Gastroenterol Hepatol 2008;20:1064-1070.

  • 19. Mantry PS, Munsaf S. Does the addition of rifaximin to lactulose reduce the severity of hepatic encephalopathy? A single-center experience [abstract]. Hepatology 2008;48:517A, #472.

  • 20. Ahmad I, Khan AA, Alam A, Dilshad A, Butt AK, Shafqat F, et al. L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy. J Coll Physicians Surg Pak 2008;18:684-687.

  • 21. Poo JL, Gongora J, Sanchez-Avila F, Aguilar-Castillo S, Garcia- Ramos G, Fernandez-Zertuche M, et al. Efficacy of oral L-ornithine-L-aspartate in cirrhotic patients with hyperammonemic hepatic encephalopathy. Results of a randomized, lactulosecontrolled study. Ann Hepatol 2006;5:281-288.


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