Human dirofilariosis: The report of subcutaneous Dirofilaria repens infection in the Slovak Republic

Open access

Abstract

Dirofilariosis is a vector-borne disease that is spreading in Europe from the southern endemic regions to the northern countries, including Slovakia. The dog parasites Dirofilaria immitis and D. repens are zoonotic agents, responsible for the development of human pulmonary and subcutaneous dirofilariosis, respectively. The present paper reports the third case of human dirofilariosis in Slovakia caused by D. repens. The pacient, a 41-year-old woman, was referred with tumour process in the subcutaneous area of the right forearm. Within 14 days the USG confirmed the rapid increase of the nodule from 20 × 10 mm to 30 × 25 mm. The surgical extirpation of the tumour was indicated. Histological examination revealed the formation with eosinofilic rime and the presence of a worm in the centre, detected as D. repens.

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • [1] Bábal P. Kobzová D. Novák I. Dubinský P. Jalili N. (2008): First case of cutaneous human dirofilariosis in Slovak Republic. Bratisl. Med. J. 109: 486–488

  • [2] Espinóza E. Cordero M. Muro A. Lorente F. Simón F. (1993): Anti-Dirofilaria immitis IgE: seroepidemiology and seasonal-variation in an exposed humanpopulation. Trop. Med. Parasitol. 44: 172–176

  • [3] Fernando S. D. Ihalamulla R. L. De Silva W. A. (2000): Male and female filarial worms Dirofilaria (Nochtiella) repens recovered from the scrotum. Ceylon Med. J. 45: 131–132

  • [4] Genchi C. Rinaldi L. Mortarino M. Genchi M. Cringoli G. (2009): Climate and Dirofilaria infection in Europe. Vet. Parasitol. 163: 286–292 http://dx.doi.org/10.1016/j.vetpar.2009.03.026

  • [5] González-Miguel J. Rosario L. Rota-Nodari E. Morchón R. Simón F. (2010): Identification of immunoreactive proteins of Dirofilaria immitis and D. repens recognized by sera from patients with pulmonary and subcutaneous dirofilariosis. Parasitol. Int. 59: 248–256 http://dx.doi.org/10.1016/j.parint.2010.02.010

  • [6] Harrus S. Baneth G. (2005): Drivers for the emergence and re-emergence of vector-borne protozoal and bacterial diseases. Int. J. Parasitol. 35: 1309–1318 http://dx.doi.org/10.1016/j.ijpara.2005.06.005

  • [7] Kramer L. H. Kartashev V. V. Grandi G. Morchon R. Nagornii S. A. Karanis P. Simón F. (2007): Human subcutaneous dirofilariasis Russia. Emerg. Infect. Dis. 13: 150–152 http://dx.doi.org/10.3201/eid1301.060920

  • [8] MacDougal L. T. Magoon C. C. Fritsche T. R. (1992): Dirofilaria repens manifesting as a breast nodule — diagnostic problems and epidemiologic considerations. Am. J. Clin. Pathol. 97: 625–630

  • [9] Medlock J. M. Barrass I. Kerrod E. Taylor M.A. Leach S. (2007): Analysis of climatic predictions for extrinsic incubation of Dirofilaria in the United Kingdom. Vector-Borne Zoonot. 7: 4–14 http://dx.doi.org/10.1089/vbz.2006.0564

  • [10] Miterpáková M. Antolová D. Hurníková Z. Dubinský P. (2008): Dirofilariosis in Slovakia — a new ende mic area in Central Europe. Helminthologia 45: 20–23 http://dx.doi.org/10.2478/s11687-008-0003-6

  • [11] Miterpáková M. Antolová D. Hurníková Z. Dubinský P. Pavlačka A. Németh J. (2010): Dirofilaria infections in working dogs in Slovakia. J. Helminthol. 84: 173–176 http://dx.doi.org/10.1017/S0022149X09990496

  • [12] Muro A. Genchi C. Cordero M. Simón F. (1999): Human dirofilariasis in the European union. Parasitol. Today 15: 386–389 http://dx.doi.org/10.1016/S0169-4758(99)01496-9

  • [13] Oleaga A. Peréz-Sanchéz R. Pages E. Marcosatxutegi C. Simón F. (2009): Identification of immunoreactive proteins from the dog heartworm (Dirofilaria immitis) differentially recognized by the sera from dogs with patent or occult infections. Mol. Biochem. Parasit. 166: 134–141 http://dx.doi.org/10.1016/j.molbiopara.2009.03.005

  • [14] Ondriska F. Lengyel D. Miterpáková M. Lengyelová B. Strehárová A. Dubinský P. (2010): Human dirofilariosis in the Slovak republic — a case report. Ann. Agr. Env. Med. 17: 169–171

  • [15] Pampiglione S. Rivasi F. (2007): Human dirofilariasis due to Dirofilaria (Nochtiella) repens: an update of world literature from 1995 to 2000. In Genchi C. Ronaldi L. Cringoli G. (Eds.): Dirofilaria immitis and D. repens in dog and cat and human infections. Italia Rolando Editore; 2007 pp. 81–116

  • [16] Pampiglione S. Rivasi F. Gustinelli A. (2009): Dirofilarial human cases in the Old World attributed to Dirofilaria immitis: a critical analysis. Histopathology 54: 192–204 http://dx.doi.org/10.1111/j.1365-2559.2008.03197_a.x

  • [17] Simón F. Morchon R. González-Miguel J. Marcos-Atxutegi C. Siles-Lucas M. (2009): What is new about animal and human dirofilariosis? Trends Parasitol. 25: 404–409 http://dx.doi.org/10.1016/j.pt.2009.06.003

  • [18] Svobodová V. Svobodová Z. Beladičová V. Valentová D. (2005): First cases of canine dirofilariosis in Slovakia: a case report. Vet. Med. - Czech. 50: 510–512

  • [19] Szénási Z. Kovács A. H. Pampiglione S. Fioravanti M. L. Kucsera I. Tánczos B. Tiszlavicz L. (2008): Human dirofilariosis in Hungary: an emerging zoonosis in central Europe. Wien. Klin. Wochenschr. 120: 96–102 http://dx.doi.org/10.1007/s00508-008-0928-2

Search
Journal information
Impact Factor


IMPACT FACTOR 2018: 0.731
5-year IMPACT FACTOR: 0.634

CiteScore 2018: 0.8

SCImago Journal Rank (SJR) 2018: 0.398
Source Normalized Impact per Paper (SNIP) 2018: 0.554

Target audience: researchers in the field of human, veterinary medicine and natural science
Cited By
Metrics
All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 182 119 4
PDF Downloads 87 72 5