Physical Activity and Gastrointestinal Cancer Risk: A Review

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Introduction: Western lifestyle characterized by increased consumption of red meat, fat, processed food, smoking, alcohol drinking, lower consumption of vegetables and physical inactivity has been associated with a higher gastrointestinal cancer risk. Digestive system cancers are diagnosed at late stages when they show poor response to treatment and are associated with a high mortality rate. Colorectal, gastric, esophageal and pancreatic cancers are among the most common cancers worldwide. Studies show that more than 50% of gastrointestinal cancers develop as a result of inappropriate lifestyle. An inverse association between physical activity and many chronic diseases has been proved so far. However, the association between physical activity and some gastrointestinal cancers is still controversial. This study was aimed to determine the association between physical activity and gastrointestinal cancers risk.

Methods: We conducted a comprehensive search of English and Persian databases from February 2007 till December 2017, for studies investigating the association of physical activity and risk of gastrointestinal cancers. Finally, after reading full text of articles, 123 studies were included.

Results: Physical activity can be helpful in reducing the risk of gastrointestinal cancer, especially colon and pancreatic cancers. The risk reduction is not similar for different types of gastrointestinal cancers and also among males and females.

Conclusion: Different types of physical activity are associated with a lower risk of gastrointestinal cancer. However, it is unknown which type and intensity of physical activity are associated with a protective effect against gastro-intestinal cancer.

1. Keum N, Bao Y, Smith-Warner SA et al. Association of Physical Activity by Type and Intensity With Digestive System Cancer Risk. JAMA oncology. 2016;2(9):1146-53.

2. Iswarya SK, Premarajan KC, Kar SS et al. Risk factors for the development of colorectal carcinoma: A case control study from South India. World J Gastrointest Oncol. 2016;8(2):207-14.

3. Huerta JM, Navarro C, Chirlaque MD et al. Prospective study of physical activity and risk of primary adenocarcinomas of the oesophagus and stomach in the EPIC (European Prospective Investigation into Cancer and nutrition) cohort. CCC. 2010;21(5):657-69.

4. Winzer BM, Paratz JD, Reeves MM, Whiteman DC. Exercise and the Prevention of Oesophageal Cancer (EPOC) study protocol: a randomized controlled trial of exercise versus stretching in males with Barrett’s oesophagus. BMC cancer. 2010;10:292.

5. Yang CS, Chen X, Tu S. Etiology and Prevention of Esophageal Cancer. Gastrointestinal tumors. 2016;3(1):3-16.

6. Spence RR, Heesch KC, Brown WJ. A systematic review of the association between physical activity and colorectal cancer risk. Scand J Med Sci Sports. 2009;19(6):764-81.

7. Wen XY. Salt taste sensitivity, physical activity and gastric cancer. APJCP. 2010;11(6):1473-7.

8. Chen Y, Yu C, Li Y. Physical activity and risks of esophageal and gastric cancers: a meta-analysis. PloS one. 2014;9(2):e88082.

9. Farris MS, Mosli MH, McFadden AA et al. The Association between Leisure Time Physical Activity and Pancreatic Cancer Risk in Adults: A Systematic Review and Meta-analysis. Cancer Epidemiol, Biomarkers Prev. 2015;24(10):1462-73.

10. Nothlings U, Wilkens LR, Murphy SP et al. Body mass index and physical activity as risk factors for pancreatic cancer: the Multiethnic Cohort Study. CCC. 2007;18(2):165-75.

11. Shephard RJ. Cancers of the Esophagus and Stomach: Potential Mechanisms behind the Beneficial Influence of Physical Activity. Clini J Sport Med. 2017;27(4):415-21.

12. Etemadi A, Golozar A, Kamangar F et al. Large body size and sedentary lifestyle during childhood and early adulthood and esophageal squamous cell carcinoma in a high-risk population. Ann Oncol. 2012;23(6):1593-600.

13. Lee YY, Derakhshan MH. Environmental and lifestyle risk factors of gastric cancer. Arch Irani Med. 2013;16(6):358-65.

14. Brenner DR, Wozniak MB, Feyt C et al. Physical activity and risk of pancreatic cancer in a central European multicenter case-control study. CCC. 2014;25(6):669-81.

15. Bailie L, Loughrey MB, Coleman HG. Lifestyle Risk Factors for Serrated Colorectal Polyps: A Systematic Review and Meta-analysis. Gastroenterology. 2017;152(1):92-104.

16. Mahfouz EM, Sadek RR, Abdel-Latief WM et al. The role of dietary and lifestyle factors in the development of colorectal cancer: case control study in Minia, Egypt. Central Eur J Publ Health. 2014;22(4):215-22.

17. Watson AJ, Collins PD. Colon cancer: a civilization disorder. Digestive diseases (Basel, Switzerland). 2011;29(2):222-8.

18. Gingras D, Beliveau R. Colorectal cancer prevention through dietary and lifestyle modifications. Cancer Microenviron. 2011;4(2):133-9.

19. Zhang J, Dhakal IB, Gross MD et al. Physical activity, diet, and pancreatic cancer: a population-based, case-control study in Minnesota. Nutr Cancer. 2009;61(4):457-65.

20. Leitzmann M, Powers H, Anderson AS et al. European Code against Cancer 4th Edition: Physical activity and cancer. Cancer Epidemiol. 2015;39 Suppl 1:S46-55.

21. Knight JA. Physical inactivity: Associated diseases and disorders. Ann Clin Laboratory Sci. 2012;42(3):320-37.

22. Namasivayam V, Lim S. Recent advances in the link between physical activity, sedentary behavior, physical fitness, and colorectal cancer. F1000Research. 2017;6.

23. Moore SC, Lee IM, Weiderpass E et al. Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults. JAMA Int Med. 2016;176(6):816-25.

24. Cook MB, Matthews CE, Gunja MZ et al. Physical activity and sedentary behavior in relation to esophageal and gastric cancers in the NIH-AARP cohort. PloS one. 2013;8(12):e84805.

25. Kruk J, Czerniak U. Physical activity and its relation to cancer risk: updating the evidence. APJCP. 2013;14(7):3993-4003.

26. Howard RA, Freedman DM, Park Y et al. Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health Study. CCC. 2008;19(9):939-53.

27. Wolin KY, Lee IM, Colditz GA et al. Leisure-time physical activity patterns and risk of colon cancer in women. Int J Cancer. 2007;121(12):2776-81.

28. Stolzenberg-Solomon RZ, Adams K, Leitzmann M et al. Adiposity, physical activity, and pancreatic cancer in the National Institutes of Health-AARP Diet and Health Cohort. Am J Epidemiol. 2008;167(5):586-97.

29. Liu L, Shi Y, Li T et al. Leisure time physical activity and cancer risk: evaluation of the WHO’s recommendation based on 126 high-quality epidemiological studies. British J Sports Med. 2016;50(6):372-8.

30. Psaltopoulou T, Ntanasis-Stathopoulos I, Tzanninis IG et al. Physical Activity and Gastric Cancer Risk: A Systematic Review and Meta-Analysis. Clin J Sport Med. 2016;26(6):445-64.

31. Nunez C, Bauman A, Egger S et al. Obesity, physical activity and cancer risks: Results from the Cancer, Lifestyle and Evaluation of Risk Study (CLEAR). Cancer Epidemiol. 2017;47:56-63.

32. Singh S, Devanna S, Edakkanambeth Varayil J et al. Physical activity is associated with reduced risk of esophageal cancer, particularly esophageal adenocarcinoma: a systematic review and meta-analysis. BMC Gastroenterology. 2014;14:101.

33. Leitzmann MF, Koebnick C, Freedman ND et al. Physical activity and esophageal and gastric carcinoma in a large prospective study. Am J Prev Med. 2009;36(2):112-9.

34. Winzer BM, Paratz JD, Whitehead JP et al. The feasibility of an exercise intervention in males at risk of oesophageal adenocarcinoma: a randomized controlled trial. PLoS One. 2015;10(2):e0117922.

35. Behrens G, Jochem C, Keimling M et al. The association between physical activity and gastroesophageal cancer: systematic review and meta-analysis. Eur J Epidemiol. 2014;29(3):151-70.

36. Castro C, Peleteiro B, Lunet N. Modifiable factors and esophageal cancer: a systematic review of published meta-analyses. J Gastroenterol. 2017:1-15.

37. Realdon S, Antonello A, Arcidiacono D et al. Adherence to WCRF/AICR lifestyle recommendations for cancer prevention and the risk of Barrett’s esophagus onset and evolution to esophageal adenocarcinoma: results from a pilot study in a high-risk population. Eur J Nutr. 2016;55(4):1563-71.

38. Balbuena L, Casson AG. Physical activity, obesity and risk for esophageal adenocarcinoma. Future oncology (London, England). 2009;5(7):1051-63.

39. Parent ME, Rousseau MC, El-Zein M et al. Occupational and recreational physical activity during adult life and the risk of cancer among men. Cancer Epidemiol. 2011;35(2):151-9.

40. Abioye AI, Odesanya MO, Abioye AI, Ibrahim NA. Physical activity and risk of gastric cancer: a meta-analysis of observational studies. Br J Sports Med. 2015;49(4):224-9.

41. Den Hoed CM, Kuipers EJ. Gastric Cancer: How Can We Reduce the Incidence of this Disease? Current Gastroenterol Rep. 2016;18(7):1-8.

42. Baroudi O, Chaaben AB, Mezlini A et al. Impact of lifestyle factors and nutrients intake on occurrence of gastrointestinal cancer in Tunisian population. Tumor Biology. 2014;35(6):5815-22.

43. De Jonge PJF, Wolters LMM, Steyerberg EW et al. Environmental risk factors in the development of adenocarcinoma of the oesophagus or gastric cardia: A cross-sectional study in a Dutch cohort. Alimen Pharmacol Ther. 2007;26(1):31-9.

44. Buckland G, Travier N, Huerta JM et al. Healthy lifestyle index and risk of gastric adenocarcinoma in the EPIC cohort study. Int J Cancer. 2015;137(3):598-606.

45. Campbell PT, Sloan M, Kreiger N. Physical activity and stomach cancer risk: The influence of intensity and timing during the lifetime. Eur J Cancer. 2007;43(3):593-600.

46. Singh S, Varayil JE, Devanna S et al. Physical activity is associated with reduced risk of gastric cancer: A systematic review and meta-analysis. Cancer Prev Res. 2014;7(1):12-22.

47. Huerta JM, Chirlaque MD, Molina AJ et al. Physical activity domains and risk of gastric adenocarcinoma in the MCC-Spain case-control study. PLoS ONE. 2017;12(7).

48. Yun YH, Lim MK, Won YJ et al. Dietary preference, physical activity, and cancer risk in men: national health insurance corporation study. BMC cancer. 2008;8:366.

49. Sjodahl K, Jia C, Vatten L et al. Body mass and physical activity and risk of gastric cancer in a population-based cohort study in Norway. Cancer Epidemiol, Biomarkers Prev. 2008;17(1):135-40.

50. Barone E, Corrado A, Gemignani F, Landi S. Environmental risk factors for pancreatic cancer: an update. Arch Toxicol. 2016;90(11):2617-42.

51. Behrens G, Jochem C, Schmid D et al. Physical activity and risk of pancreatic cancer: a systematic review and meta-analysis. Eur J Epidemiol. 2015;30(4):279-98.

52. Noor NM, Banim PJ, Luben RN et al. Investigating Physical Activity in the Etiology of Pancreatic Cancer: The Age at Which This Is Measured Is Important and Is Independent of Body Mass Index. Pancreas. 2016;45(3):388-93.

53. O’Rorke MA, Cantwell MM, Cardwell CR et al. Can physical activity modulate pancreatic cancer risk? a systematic review and meta-analysis. Int JCancer. 2010;126(12):2957-68.

54. Calton BA, Stolzenberg-Solomon RZ, Moore SC et al. A prospective study of physical activity and the risk of pancreatic cancer among women (United States). BMC cancer. 2008;8:63.

55. Heinen MM, Verhage BA, Goldbohm RA et al. Physical activity, energy restriction, and the risk of pancreatic cancer: a prospective study in the Netherlands. Am J Clin Nut. 2011;94(5):1314-23.

56. Maisonneuve P, Lowenfels AB. Risk factors for pancreatic cancer: A summary review of meta-analytical studies. Int J Epidemiol. 2015;44(1):186-98.

57. Lin Y, Kikuchi S, Tamakoshi A et al. Obesity, physical activity and the risk of pancreatic cancer in a large Japanese cohort. Intl J Cancer. 2007;120(12):2665-71.

58. Kushi LH, Doyle C, McCullough M et al. American Cancer Society guidelines on nutrition and physical activity for cancer prevention: Reducing the Risk of Cancer with Healthy Food Choices and Physical Activity. CA Cancer J Clin. 2012;62(1):30-67.

59. Bao Y, Michaud DS. Physical activity and pancreatic cancer risk: a systematic review. Cancer Epidemiol. 2008;17(10):2671-82.

60. Stevens RJ, Roddam AW, Spencer EA et al. Factors associated with incident and fatal pancreatic cancer in a cohort of middle-aged women. Int J Cancer. 2009;124(10):2400-5.

61. Sehdev A, O’Neil BH. The Role of Aspirin, Vitamin D, Exercise, Diet, Statins, and Metformin in the Prevention and Treatment of Colorectal Cancer. Curr Treat Options oncol. 2015;16(9):43.

62. Aran V, Victorino AP, Thuler LC, Ferreira CG. Colorectal Cancer: Epidemiology, Disease Mechanisms and Interventions to Reduce Onset and Mortality. Clin Colorectal Cancer. 2016;15(3):195-203.

63. Golshiri P, Rasooli S, Emami M, Najimi A. Effects of Physical Activity on Risk of Colorectal Cancer: A Case-control Study. Int J Prev Med. 2016;7:32.

64. Mohandas KM. Colorectal cancer in India: Controversies, enigmas and primary prevention. Indian J Gastroenterol. 2011;30(1):3-6.

65. Sanchez NF, Stierman B, Saab S et al. Physical activity reduces risk for colon polyps in a multiethnic colorectal cancer screening population. BMC research notes. 2012;5:312.

66. Qasim A, O’Morain C. Primary prevention of colorectal cancer: Are we closer to reality? Eur J Gastroenterol Hepatology. 2010;22(1):9-17.

67. Lieberman D. Screening, Surveillance, and Prevention of Colorectal Cancer. Gastrointest Endosc Clin N Am. 2008;18(3):595-605.

68. Omran S, Barakat H, Muliira JK, McMillan S. Dietary and Lifestyle Risk Factors for Colorectal Cancer in Apparently Healthy Adults in Jordanian Hospitals. J Cancer Educ. 2015.

69. Crosara Teixeira M, Braghiroli MI, Sabbaga J, Hoff PM. Primary prevention of colorectal cancer: myth or reality? World J Gastroenterol. 2014;20(41):15060-9.

70. Wei EK, Colditz GA, Giovannucci EL et al. Cumulative risk of colon cancer up to age 70 years by risk factor status using data from the nurses’ health study. Am J Epidemiol. 2009;170(7):863-72.

71. Erdrich J, Zhang X, Giovannucci E, Willett W. Proportion of colon cancer attributable to lifestyle in a cohort of US women. Cancer Causes Control. 2015;26(9):1271-9.

72. Huxley RR, Ansary-Moghaddam A, Clifton P et al. The impact of dietary and lifestyle risk factors on risk of colorectal cancer: A quantitative overview of the epidemiological evidence. Int J Cancer. 2009;125(1):171-80.

73. Boyle T, Keegel T, Bull F et al. Physical activity and risks of proximal and distal colon cancers: a systematic review and meta-analysis. J Nat Cancer Inst. 2012;104(20):1548-61.

74. Robsahm TE, Aagnes B, Hjartaker A et al. Body mass index, physical activity, and colorectal cancer by anatomical sub-sites: a systematic review and meta-analysis of cohort studies. Eur J Cancer Prev. 2013;22(6):492-505.

75. Nilsen TI, Romundstad PR, Petersen H et al. Recreational physical activity and cancer risk in subsites of the colon (the Nord-Trondelag Health Study). Cancer Epidemiol, biomarkers Prev. 2008;17(1):183-8.

76. Lee KJ, Inoue M, Otani T et al. Physical activity and risk of colorectal cancer in Japanese men and women: the Japan Public Health Center-based prospective study. Cancer causes & control: CCC. 2007;18(2):199-209.

77. Odegaard AO, Koh WP, Yuan JM. Combined lifestyle factors and risk of incident colorectal cancer in a Chinese population. Cancer Prev Res. 2013;6(4):360-7.

78. Song JH, Kim YS, Yang SY et al. Physical activity and other lifestyle factors in relation to the prevalence of colorectal adenoma: a colonoscopy-based study in asymptomatic Koreans. CCC. 2013;24(9):1717-26.

79. Mai PL, Sullivan-Halley J, Ursin G et al. Physical activity and colon cancer risk among women in the California Teachers Study. Cancer Epidemiol, Biomarkers Prev. 2007;16(3):517-25.

80. Eaglehouse YL, Koh WP, Wang R et al. Physical activity, sedentary time, and risk of colorectal cancer: the Singapore Chinese Health Study. Eur Jo Cancer Prev. 2017.

81. Wang FW, Hsu PI, Chuang HY et al. Prevalence and risk factors of asymptomatic colorectal polyps in Taiwan. Gastroenterol Res Practice. 2014;2014.

82. Øines M, Helsingen LM, Bretthauer M, Emilsson L. Epidemiology and risk factors of colorectal polyps. Best Practice and Research: Clin Gastroenterol. 2017;31(4):419-24.

83. Fu Z, Shrubsole MJ, Smalley WE et al. Lifestyle factors and their combined impact on the risk of colorectal polyps. Am J Epidemiol. 2012;176(9):766-76.

84. Wolin KY, Yan Y, Colditz GA. Physical activity and risk of colon adenoma: a meta-analysis. Br J Cancer. 2011;104(5):882-5.

85. Jayasekara H, Reece JC, Buchanan DD et al. Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis. J Gastroenterol Hepatol (Australia). 2017;32(2):301-26.

86. Haque TR, Bradshaw PT, Crockett SD. Risk Factors for Serrated Polyps of the Colorectum. Dig Dis Sci. 2014;59(12):2874-89.

87. Wolin KY, Yan Y, Colditz GA, Lee IM. Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer. 2009;100(4):611-6.

88. Tayyem RF, Shehadeh IN, Abumweis SS et al. Physical inactivity, water intake and constipation as risk factors for colorectal cancer among adults in Jordan. APJCP. 2013;14(9):5207-12.

89. Naing C, Lai PK, Mak JW. Immediately modifiable risk factors attributable to colorectal cancer in Malaysia. BMC Public Health. 2017;17(1).

90. Thrumurthy SG, Thrumurthy SSD, Gilbert CE et al. Colorectal adenocarcinoma: Risks, prevention and diagnosis. BMJ (Online). 2016;354.

91. White V, Miller R. Colorectal cancer: prevention and early diagnosis. Medicine. 2007;35(6):297-301.

92. Johnson CM, Wei C, Ensor JE et al. Meta-Analyses of colorectal cancer risk factors. Cancer Causes Control. 2013;24(6):1207-22.

93. Takahashi H, Kuriyama S, Tsubono Y et al. Time spent walking and risk of colorectal cancer in Japan: The Miyagi Cohort Study. Eur J Cancer Prev. 2007;16(5):403-8.

94. Rosato V, Bosetti C, Levi F et al. Risk factors for young-onset colorectal cancer. CCC. 2013;24(2):335-41.

95. Boyle T. Physical Activity and Colon Cancer: Timing, Intensity, and Sedentary Behavior. Am J Lifestyle Med. 2012;6(3):204-15.

96. Moradi T, Gridley G, Björk J et al. Occupational physical activity and risk for cancer of the colon and rectum in Sweden among men and women by anatomic subsite. Eur J Cancer Prev. 2008;17(3):201-8.

97. Harriss DJ, Atkinson G, Batterham A et al. Lifestyle factors and colorectal cancer risk (2): a systematic review and meta-analysis of associations with leisure-time physical activity. Colorectal dis. 2009;11(7):689-701.

98. Wolin KY, Patel AV, Campbell PT et al. Change in physical activity and colon cancer incidence and mortality. Cancer Epidemiol, Biomarkers Prev. 2010;19(12):3000-4.

99. Halle M, Schoenberg MH. Physical activity in the prevention and treatment of colorectal carcinoma. Dtsch Arztebl Int. 2009;106(44):722-7.

100. Alazzeh AY, Azzeh FS. Active lifestyle patterns reduce the risk of colorectal cancer in the Mecca region, Saudi Arabia: a case–control study. Eur J Cancer Prev. 2017.

101. Fang JY, Shi YQ, Chen YX et al. Chinese consensus on the prevention of colorectal cancer (2016, Shanghai). J Dig Dis. 2017;18(2):63-83.

102. Hang J, Cai B, Xue P et al. The Joint effects of lifestyle factors and comorbidities on the risk of colorectal cancer: A large Chinese retrospective case-control study. PLoS ONE. 2015;10(12).

103. Mehta M, Shike M. Diet and physical activity in the prevention of colorectal cancer. JNCCN. 2014;12(12):1721-6.

104. Azeem K, Ševčíková J, Kyselý Z et al. Primary and secondary prevention of colorectal cancer in the Czech Republic. Prz Gastroenterol. 2016;11(1):1-5.

105. Marshall JR. Prevention of Colorectal Cancer: Diet, Chemoprevention, and Lifestyle. Gastroenterol Clin N Am. 2008;37(1):73-82.

106. Chan AT, Giovannucci EL. Primary Prevention of Colorectal Cancer. Gastroenterol. 2010;138(6):2029-43.e10.

107. Roncucci L, Mariani F. Prevention of colorectal cancer: How many tools do we have in our basket? Eur J Int Med. 2015;26(10):752-6.

108. Boyle T, Bull F, Fritschi L, Heyworth J. Resistance training and the risk of colon and rectal cancers. Cancer Causes and Control. 2012;23(7):1091-7.

109. Parkin DM, Olsen AH, Sasieni P. The potential for prevention of colorectal cancer in the UK. Eur J Cancer Prev. 2009;18(3):179-90.

110. Simons CC, Hughes LA, van Engeland M et al. Physical activity, occupational sitting time, and colorectal cancer risk in the Netherlands cohort study. Am J Epidemiol. 2013;177(6):514-30.

111. Gorczyca AM, Eaton CB, LaMonte MJ et al. Association of physical activity and sitting time with incident colorectal cancer in postmenopausal women. Eur J Cancer Prev. 2017.

112. Yarnall JM, Crouch DJM, Lewis CM. Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancer. Cancer Epidemiol. 2013;37(3):324-9.

113. Ranadive IN, Sussman DA. Prevention of colorectal cancer: The future is now. Curr Colorectal Cancer Rep. 2014;10(1):84-93.

114. Brenner DR. Cancer incidence due to excess body weight and leisure-time physical inactivity in Canada: Implications for prevention. Prev Med. 2014;66:131-9.

115. Dahham SS, Majid AMA. The impact of life style and nutritional components in primary prevention of colorectal cancer. J Appl Pharm Sci. 2016;6(9):237-44.

116. Miles L. Physical activity and the prevention of cancer: A review of recent findings. Nutrition Bulletin. 2007;32(3): 250-82.

117. Rasool S, Kadla SA, Rasool V, Ganai BA. A comparative overview of general risk factors associated with the incidence of colorectal cancer. Tumor Biology. 2013;34(5):2469-76.

118. Hughes LAE, Simons CCJM, van den Brandt PA et al. Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP). PLoS ONE. 2011;6(4).

119. Durko L, Malecka-Panas E. Lifestyle Modifications and Colorectal Cancer. Curr Colorectal Cancer Reports. 2014;10:45-54.

120. Schoenberg MH. Physical Activity and Nutrition in Primary and Tertiary Prevention of Colorectal Cancer. Vis Med. 2016;32(3):199-204.

121. Trojian TH, Mody K, Chain P. Exercise and colon cancer: Primary and secondary prevention. Curr Sports Med Reports. 2007;6(2):120-4.

122. Fuemmeler BF, Pendzich MK, Tercyak KP. Weight, dietary behavior, and physical activity in childhood and adolescence: Implications for adult cancer risk. Obesity Facts. 2009;2(3):179-86.

123. Friedenreich CM, Neilson HK, Lynch BM. State of the epidemiological evidence on physical activity and cancer prevention. Eur J Cancer (Oxford, England: 1990). 2010;46(14):2593-604.

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