Commentary. What is the risk of rabies transmission from patients to health care staff?

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Admission of a human rabies case to hospital often creates great anxiety among staff that fear contamination. The care of a rabies patient requires only standard infectious precautions consisting of basic preventive measure applied in many other common diseases. This should be sufficient to prevent transmission to staff. Therefore, prevention of anxiety among health care workers should be an achievable goals.

1. Rabies [Internet]. 2011 [cited 2011 Oct 12]. Available from:

2. Fekadu M, Shaddock JH, Baer GM. Excretion of rabies virus in saliva of rabid dogs. J Infect Dis. 1982; 145:715-9.

3. Vaughn JB, Gerhardt P, Paterson JCH. Excretion of street rabies virus in saliva of cats. JAMA. 1963; 184: 705-8.

4. Wacharapluesadee S, Phumesin P, Supavonwong P, Khawplod P, Interut N, Hemachudha T. Comarative detection of rabies RNA by NASBA, Real time PCR and conventional PCR. J Virol Methods. 2011; 175: 278-82.

5. Wacharapluesadee S, Hemachudha T. Antemortem and post-mortem diagnosis of rabies by nucleic acid amplification test. Expert Rev Mol Diagn. 2010; 10: 207-18.

6. Sitprija V, Sriaroon C, Lumlertdaecha B, Wacharapluesadee S, Phumesin P, Khawplod P, et al. Does contact with urine and blood from a rabid dog represent a rabies risk? Clin Infect Dis. 2003; 37: 1399-400.

7. Basic human health considerations and bats [Internet]. 2010 [cited 2011 Oct 5]. Available from:

8. Rhabdovirus (Rabies Virus) [Internet]. 2011 [cited 2011 Oct 6]. Available from:

9. White LA, Chappell WA. Inactivation of rabies virus in reagents used for the fluorescent antibody test. J Clin Microbiol. 1982; 16:253-6.

10. Fekadu M, Endeshaw T, Wondimagegnehu A, Bogale Y, Teshager T, Olson JG. Possible human-tohuman transmission of rabies in Ethiopia. Ethiop Med J. 1996; 34:123-7.

11. Sipahioðlu U, Alpaut S. Transplacental rabies in humans. Mikrobiyol Bul. 1985; 19:95-9.

12. Palmirksi W, Karlowski Z. Wyniki szczepien ochronnych wedlug metody Pasteur’a wroku 1898. Medycyna. 1900; 28:70-4.

13. World Health Organization. WHO expert committee on rabies. World Health Organ Tech Rep Ser. 2005; 931:1-121.

14. Gode GR, Bhide NK. Two rabies deaths after corneal grafts from one donor. Lancet. 1988; 2:791.

15. Centers for Disease Control and Prevention. Humanto- human transmission of rabies via a corneal transplant - France. MMWR. 1980; 29:25-6.

16. Houff SA, Burton RC, Wilson RW, Henson TE, London WT, Baer GM, et al. Human-to-human transmission of rabies virus by corneal transplant. N Engl J Med. 1979; 300:603-4.

17. World Health Organization. Two rabies cases following corneal transplantation. Weekly Epidemiol Rec. 1994; 69:330.

18. Baer GM, Shaddock JH, Houff SA, Harrison AK, Gardner JJ. Human rabies transmitted by corneal transplant. Arch Neurol. 1982; 39:103-7.

19. Javadi MA, Fayaz A, Mirdehghan SA, Ainollahi B. Transmission of rabies by corneal graft. Cornea. 1996; 15:431-3.

20. Srinivasan A, Burton EC, Kuehnert MJ, Rupprecht C, Sutker WL, Ksiazek TG, et al. Transmission of rabies virus from an organ donor to four transplant recipients. N Engl J Med. 2005; 352:1103-11.

21. Hellenbrand W, Meyer C, Rasch G, Steffens I, Ammon A. Cases of rabies in Germany following organ transplantation. Euro Surveill. 2005; 10: E050224.

22. Centers for Disease Control and Prevention. Update: investigation of rabies infections in organ donor and transplant recipients-Alabama, Arkansas, Oklahoma, and Texas. MMWR. 2004; 53:615-6.

23. Burton EC, Burns DK, Opatowsky MJ, El-Feky WH, Fischbach B, Melton L, et al. Rabies encephalomyelitis: clinical, neuroradiological, and pathological findings in 4 transplant recipients. Arch Neurol. 2005; 62: 873-82.

24. Sudarshan MK, Narayana DH. A survey of hospitals managing human rabies cases in India. Indian Journal of Public Health. 2010; 54:40-1.

25. Garner JS, Simmons BP. Guidelines for isolation precautions in hospitals. Infect Control. 1983; 4 (Suppl):245-325.

26. Anderson LJ, Winkler WG. Aqueous quaternary ammonium compounds and rabies treatment. J Infect Dis. 1979; 139:494-5.

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