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Comparison of the solid phase and liquid-liquid extraction methods for methadone determination in human serum and whole blood samples using gas chromatography/mass spectrometry


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1. El-Beqqali A, Abdel-Rehim M. Quantitative analysis of methadone in human urine samples by microextraction in packed syringe-gas chromatography-mass spectrometry (MEPS-GC-MS). J Separ Sci 2007;30:2501-5. doi: 10.1002/jssc.200700067Search in Google Scholar

2. Kharasch ED. Current concepts in methadone metabolism and transport. Clin Pharmacol Drug Dev 2017;6:125-34. doi: 10.1002/cpdd.326Search in Google Scholar

3. Samanidou VF, Anastasiadou K, Papadoyannis IN. Development and validation of a rapid HPLC method for the determination of methadone and its main metabolite EDDP in biological fluids, following SPE. J Liq Chromatogr Relat Technol 2006;29:889-902. doi: 10.1080/10826070500531433Search in Google Scholar

4. Juhascik MP, Jenkins AJ. Comparison of liquid/liquid and solid-phase extraction for alkaline drugs. J Chromatogr Sci 2009;47:553-7. PMID: 1977272610.1093/chromsci/47.7.553Search in Google Scholar

5. Diong SH, Mohd Yusoff NS, Sim MS, Raja Aziddin RE, Chik Z, Rajan P, Abdul Rashid R, Chemi N, Mohamed Z. Quantitation of methadone and metabolite in patients under maintenance treatment. J Anal Toxicol 2014;38:660-6. doi: 10.1093/jat/bku096Search in Google Scholar

6. Hsu Y-C, Chen B-G, Yang S-C, Wang Y-S, Huang S-P, Huang M-H, Chen TJ, Liu HC, Lin DL, Liu RH, Jones AW. Methadone concentrations in blood, plasma, and oral fluid determined by isotope-dilution gas chromatography-mass spectrometry. Anal Bioanal Chem 2013;405:3921-8. doi: 10.1007/s00216-012-6460-2Search in Google Scholar

7. Rudaz S, Veuthey JL. Stereoselective determination of methadone in serum by HPLC following solid-phase extraction on disk. J Pharm Biomed Anal 1996;14:1271-9. PMID: 881804510.1016/0731-7085(95)01660-0Search in Google Scholar

8. Nakhla DS, Hussein LA, Magdy N, Abdallah IA, Hassan HE. Precise simultaneous quantification of methadone and cocaine in rat serum and brain tissue samples following their successive i.p. administration. J Chromatogr B Analyt Technol Biomed Life Sci 2017;1048:19-29. doi: 10.1016/j. jchromb.2017.01.048Search in Google Scholar

9. Cheng YF, Neue UD, Woods LL. Novel high-performance liquid chromatographic and solid-phase extraction methods for quantitating methadone and its metabolite in spiked human urine. J Chromatogr B Biomed Sci Appl 1999;729:19-31. doi: 10.1016/S0378-4347(99)00116-4Search in Google Scholar

10. He H, Sun C, Wang XR, Pham-Huy C, Chikhi-Chorfi N, Galons H, Thevenin M, Claude JR, Warnet JM. Solid-phase extraction of methadone enantiomers and benzodiazepines in biological fluids by two polymeric cartridges for liquid chromatographic analysis. J Chromatogr B Anal Technol Biomed Life Sci 2005;814:385-91. doi: 10.1016/j.jchromb.2004.10.048Search in Google Scholar

11. Frost M, Kohler H, Blaschke G. Enantioselective determination of methadone and its main metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in serum, urine and hair by capillary electrophoresis. Electrophoresis 1997;18:1026-34. doi: 10.1002/elps.1150 180627Search in Google Scholar

12. Schmidt N, Brune K, Geisslinger G. Stereoselective determination of the enantiomers of methadone in plasma using high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 1992;583:195-200. doi: 10.1016/0378- 4347(92)80552-2Search in Google Scholar

13. Norris RL, Ravenscroft PJ, Pond SM. Sensitive highperformance liquid chromatographic assay with ultraviolet detection of methadone enantiomers in plasma. J Chromatogr B, Biomed Sci Appl 1994;661:346-50. doi: 10.1016/0378- 4347(94)00341-6Search in Google Scholar

eISSN:
0004-1254
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Journal Subjects:
Medicine, Basic Medical Science, other